cAMPS-Sp, triethylammonium salt

Name: cAMPS-Sp, triethylammonium salt
Brand: Tocris Bioscience
SKU: 1333

Tocris Bioscience, part of Bio-Techne | Catalog # 1333

Citations (4)

COA / SDS

Cell-permeable cAMP analog

Key Product Details

Chemical Name:	(S)-Adenosine, cyclic 3',5'-(hydrogenphosphorothioate) triethylammonium
Purity:	≥98%
Molecular Weight:	446.46 kDa

View Full Technical Details for cAMPS-Sp, triethylammonium salt

Technical Data
Citations

Biological Activity for cAMPS-Sp, triethylammonium salt

cAMPS-Sp, triethylammonium salt is a cell-permeable cAMP analog that activates cAMP receptor proteins such as PKA and cAMP-regulated guanine nucleotide exchange factor.

R-enantiomer also available.

Technical Data for cAMPS-Sp, triethylammonium salt

M. Wt	446.46 kDa
Formula	C₁₀H₁₂N₅O₅PS.C₆H₁₅N
Storage	Store at -20°C
Purity	≥98%
CAS Number	93602-66-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for cAMPS-Sp, triethylammonium salt

Solubility

Soluble Soluble to 100 mM in water

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References for cAMPS-Sp, triethylammonium salt

References are publications that support the biological activity of the product.

Dostmann et al. Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3',5'-cyclic phosphorothioates. J.Biol.Chem., 1990;265:10484 PMID: 2162349
Kawasaki et al. A family of cAMP-binding proteins that directly activate Rap1. Science, 1998;282:2275 PMID: 9856955
Lin et al. Ethanol inhibition of NMDA-induced responses and actute tolerance to the inhibition in rat rostral ventrolateral medulla in vivo: Involvement of cAMP-dependent protein kinases. Neuropharmacology, 2006;51:747 PMID: 16806304
O'Brian et al. A kinetic study of interactions of (R_p)- and (S_p)-adenosine cyclic 3',5'-phosphorothioates with type II bovine cardiac muscle adenosine cyclic 3',5'-phosphate dependent protein kinase. Biochemistry, 1982;21:4371 PMID: 6289880