Cariporide

Biological Activity for Cariporide

Technical Data for Cariporide

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Cariporide

References for Cariporide

References are publications that support the biological activity of the product.

• Scholz et al. Protective effects of HOE642, a selective sodium-hydrogen exchange subtype 1 inhibitor, on cardiac ischaemia and reperfusion. Cardiovasc.Res., 1995;29:260 PMID: 7736504
• Chakrabarti et al. A rapid ischemia-induced apoptosis in isolated rat hearts and its attenuation by the sodium-hydrogen exchange inhibitor HOE 642 (cariporide). J.Mol.Cell.Cardiol., 1997;29:3169 PMID: 9405190
• Teshima et al. Cariporide (HOE642), a selective Na⁺-H⁺ exchange inhibitor, inhibits the mitochondrial death pathway. Circulation, 2003;108:2275 PMID: 14568900
• Harguindey et al. Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs--an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research. J.Transl.Med., 2013;11:282 PMID: 24195657