CYM 50769

Name: CYM 50769
Brand: Tocris Bioscience
SKU: 4948

Tocris Bioscience, part of Bio-Techne | Catalog # 4948

Citations (2)

COA / SDS

Novel non-peptide NPBWR1 antagonist

Key Product Details

Description:	Novel non-peptide NPBWR1 antagonist
Alternative Names:	ML250
Chemical Name:	5-Chloro-2-(9H-fluoren-9-yl)-4-(4-methoxyphenoxy)-3(2H)-pyridazinone
Purity:	≥98% (HPLC)
Molecular Weight:	416.86

View Full Technical Details for CYM 50769

Technical Data
Citations

Biological Activity for CYM 50769

CYM 50769 is a novel non-peptide antagonist of neuropeptide W/B receptor 1 (NPBWR1, GPR7) (IC₅₀ = 0.12 μM).

Technical Data for CYM 50769

M. Wt	416.86
Formula	C₂₄H₁₇ClN₂O₃
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	1421365-63-0
PubChem ID	50904505
InChi Key	QHVSQUYCVUHYKT-UHFFFAOYSA-N
Smiles	ClC(C=N4)=C(OC5=CC=C(OC)C=C5)C(N4C2C3=C(C=CC=C3)C1=CC=CC=C12)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for CYM 50769

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	41.69	100

Preparing Stock Solutions for CYM 50769

The following data is based on the product molecular weight 416.86.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.40 mL	11.99 mL	23.99 mL
5 mM	0.48 mL	2.40 mL	4.80 mL
10 mM	0.24 mL	1.20 mL	2.40 mL
50 mM	0.05 mL	0.24 mL	0.48 mL

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Reconstitution Calculator

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References for CYM 50769

References are publications that support the biological activity of the product.

Guerrero SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists. Bioorg.Med.Chem.Lett. 2013 PMID: 23287738