DAMGO

Tocris Bioscience, part of Bio-Techne | Catalog # 1171

(1)

Citations (221)

COA / SDS

Selective μ agonist

Key Product Details

Description:	Selective μ agonist
Alternative Names:	DAGO
Chemical Name:	[D-Ala², NMe-Phe⁴, Gly-ol⁵]-enkephalin
Purity:	≥95% (HPLC)
Molecular Weight:	513.7

View Full Technical Details for DAMGO

Technical Data
Citations / Reviews (1)

Biological Activity for DAMGO

DAMGO is a highly selective peptide agonist for the μ opioid receptor.

Technical Data for DAMGO

M. Wt	513.7
Formula	C₂₆H₃₅N₅O₆
Single Letter Sequence	YAGFG (Modifications: Ala-2 = D-Ala, Phe-4 = N-methyl-Phe, Gly-5 = Gly-ol)
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	78123-71-4
PubChem ID	5462471
InChi Key	HPZJMUBDEAMBFI-WTNAPCKOSA-N
Smiles	[H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@H](C)C(=O)NCC(=O)N(C)[C@@H](CC1=CC=CC=C1)C(=O)NCCO

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for DAMGO

Solubility

Soluble to 2mg/ml in water

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References for DAMGO

References are publications that support the biological activity of the product.

Hirning Studies in vitro with ICI 174,864, [D-Pen²,D-Pen⁵]-enkephalin (DPDPE) and [D-Ala²,NMePhe⁴,Gly-ol]-enkephalin (DAGO). Neuropeptides 1985 PMID: 2987739
Fang Opioid receptors (DAGO-enkephalin, dynorphin A(1-13), BAM 22P) microinjected into the rat brainstem: comparison of their antinociceptive effect and their effect on neuronal firing in the rostral ventromedial medulla. Brain Res. 1989 PMID: 2572306