(±)-LY 395756

Name: (±)-LY 395756
Brand: Tocris Bioscience
SKU: 3272

Tocris Bioscience, part of Bio-Techne | Catalog # 3272

COA / SDS

Mixed mGlu2 agonist/ mGlu3 antagonist

Discontinued Product

3272 has been discontinued. View all Glutamate Receptor Compounds products.

Key Product Details

Description:	Mixed mGlu₂ agonist/ mGlu₃ antagonist
Chemical Name:	(1S,2S,4R,5R,6S)-rel-2-Amino-4-methylbicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Purity:	≥98% (HPLC)
Molecular Weight:	199.21

View Full Technical Details for (±)-LY 395756

Technical Data
Citations

Biological Activity for (±)-LY 395756

(±)-LY 395756 is a selective metabotropic glutamate ligand for mGlu₂and mGlu₃ receptors (K_i values are 0.165 μM and 0.302 μM respectively). Acts as an agonist at mGlu₂ and antagonist at mGlu₃. Analog of LY 354740 (Cat. No. 3246).

Technical Data for (±)-LY 395756

M. Wt	199.21
Formula	C₉H₁₃NO₄
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	852679-66-4
PubChem ID	11310142
InChi Key	BQVZICWQBFTOJX-QNDZYWSYSA-N
Smiles	N[C@]1([C@](O)=O)[C@@]2([H])[C@@]([C@@H]2[C@](O)=O)([H])[C@H](C)C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

References for (±)-LY 395756

References are publications that support the biological activity of the product.

Dominguez Methyl substitution of 2-aminobicyclo[3.1.0]hexane 2,6-dicarboxylate (LY354740) determines functional activity at metabotropic glutamate receptors: identification of a subtype selective mGlu2 receptor agonist. J.Med.Chem. 2005 PMID: 15887967

(±)-LY 395756

Tocris Bioscience, part of Bio-Techne | Catalog # 3272

Key Product Details

Biological Activity for (±)-LY 395756

Technical Data for (±)-LY 395756

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for (±)-LY 395756

Product Documents for (±)-LY 395756

COA

Certificate of Analysis

SDS

CONTACT INFORMATION

Stay Connected