DNQX disodium salt

Name: DNQX disodium salt
Brand: Tocris Bioscience
SKU: 2312

Tocris Bioscience, part of Bio-Techne | Catalog # 2312

(2)

Citations (61)

COA / SDS

Selective non-NMDA iGluR antagonist; water-soluble salt of DNQX (Cat. No. 0189)

Key Product Details

Chemical Name:	6,7-Dinitroquinoxaline-2,3-dione disodium salt
Purity:	≥98%
Molecular Weight:	296.1 kDa

View Full Technical Details for DNQX disodium salt

Technical Data
Citations / Reviews (2)

Biological Activity for DNQX disodium salt

DNQX disodium salt is a more water-soluble form of DNQX (Cat. No. 0189). DNQX is a selective non-NMDA glutamate receptor antagonist. (IC₅₀ = 0.1 μM and 0.5 μM for kainate and AMPA receptors, respectively). DNQX is a neuroleptic agent that shows pro-oxidative properties. DNQX selectively depolarizes rat thalamic reticular nucleus neurons.

Technical Data for DNQX disodium salt

M. Wt	296.1 kDa
Formula	C₈H₂N₄O₆Na₂
Storage	Desiccate at RT
Purity	≥98%
CAS Number	1312992-24-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for DNQX disodium salt

Solubility

Soluble Soluble to 100 mM in water

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References for DNQX disodium salt

References are publications that support the biological activity of the product.

Honore et al. Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science, 1988;241:701 PMID: 2899909
Watkins et al. Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists. TiPS, 1990;11:25 PMID: 2155495