Ipsapirone

Name: Ipsapirone
Brand: Tocris Bioscience
SKU: 1869

Tocris Bioscience, part of Bio-Techne | Catalog # 1869

Citations (8)

COA / SDS

Selective 5-HT1A agonist

Key Product Details

Chemical Name:	2-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3(2H)-one-1,1-dioxide
Purity:	≥99%
Molecular Weight:	401.48 kDa

View Full Technical Details for Ipsapirone

Technical Data
Citations

Biological Activity for Ipsapirone

Ipsapirone is a selective 5-HT_1A receptor agonist (K_i = 10 nM). Anxiolytic in vivo.

Technical Data for Ipsapirone

M. Wt	401.48 kDa
Formula	C₁₉H₂₃N₅O₃S
Storage	Store at RT
Purity	≥99%
CAS Number	95847-70-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Ipsapirone

Solubility

Soluble Soluble to 10 mM in DMSO

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References for Ipsapirone

References are publications that support the biological activity of the product.

Maj et al. Central action of ipsapirone, a new anxiolytic drug, on serotoninergic, noradrenergic and DArgic functions. J.Neural.Transm., 1987;70:1 PMID: 2889795
Glaser and Traber Binding of the putative anxiolytic TVX Q 7821 to hippocampal 5-hydroxytryptamine (5-HT) recognition sites. Naunyn-Schmied.Arch.Pharmacol., 1985;329:211
Traber et al. Brain serotonin receptors as a target for the putative anxiolytic TVX Q 7821. Brain Res.Bull., 1984;12:741 PMID: 6541079