L-BMAA hydrochloride

Name: L-BMAA hydrochloride
Brand: Tocris Bioscience
SKU: 2538

Tocris Bioscience, part of Bio-Techne | Catalog # 2538

Citations (1)

COA / SDS

Neurotoxic amino acid

Key Product Details

Description:	Neurotoxic amino acid
Chemical Name:	3-(Methylamino)-L-alanine hydrochloride
Molecular Weight:	154.6

View Full Technical Details for L-BMAA hydrochloride

Technical Data
Citations

Biological Activity for L-BMAA hydrochloride

L-BMAA hydrochloride is a neurotoxic glutamate agonist originally isolated from Cycas circinalis. Implicated in the pathogenesis of amyotrophic lateral sclerosis-Parkinsonism-dementia complex of Guam (Guam ALS-PD).

Technical Data for L-BMAA hydrochloride

M. Wt	154.6
Formula	C₄H₁₀N₂O₂.HCl
Storage	Store at -20°C
CAS Number	16012-55-8
PubChem ID	51358333
InChi Key	VDXYGASOGLSIDM-DFWYDOINSA-N
Smiles	N[C@@H](CNC)C(O)=O.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for L-BMAA hydrochloride

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	9.28	60

Preparing Stock Solutions for L-BMAA hydrochloride

The following data is based on the product molecular weight 154.6.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.6 mM	10.78 mL	53.90 mL	107.81 mL
3 mM	2.16 mL	10.78 mL	21.56 mL
6 mM	1.08 mL	5.39 mL	10.78 mL
30 mM	0.22 mL	1.08 mL	2.16 mL

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Reconstitution Calculator

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References for L-BMAA hydrochloride

References are publications that support the biological activity of the product.

Vega The preparation of L- and D-α-amino-β<-methylaminopropionic acids and the identification of the compound isolated from Cycas circinalis as the L-isomer. Phytochemistry
Weiss Neurotoxicity of β-N-methylamino-L-alanine (BMAA) and β-N-oxalylamino-L-alanine (BOAA) on cultured cortical neurons. Brain Res. 1989 PMID: 2551452