[Leu⁵]-Enkephalin

Name: [Leu 5 ]-Enkephalin
Brand: Tocris Bioscience
SKU: 1889

Tocris Bioscience, part of Bio-Techne | Catalog # 1889

Citations (4)

COA / SDS

Endogenous opioid agonist peptide

Key Product Details

Description:	Endogenous opioid agonist peptide
Alternative Names:	ICI 114740,Dynorphin-(1-5),YGGFL
Purity:	≥95% (HPLC)
Molecular Weight:	555.63

View Full Technical Details for [Leu⁵]-Enkephalin

Technical Data
Citations

Biological Activity for [Leu⁵]-Enkephalin

[Leu⁵]-Enkephalin is an endogenous opioid agonist peptide; inhibits electrically stimulated contractions in mouse vas deferens (IC₅₀ = 11.4 nM). Short-acting in vivo.

Technical Data for [Leu⁵]-Enkephalin

M. Wt	555.63
Formula	C₂₈H₃₇N₅O₇
Single Letter Sequence	YGGFL
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	58822-25-6
PubChem ID	461776
InChi Key	URLZCHNOLZSCCA-VABKMULXSA-N
Smiles	[H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for [Leu⁵]-Enkephalin

Solubility

Soluble to 1mg/ml in water

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References for [Leu⁵]-Enkephalin

References are publications that support the biological activity of the product.

Law and Loh ³H-Leu⁵-enkephalin specific binding to synaptic membrane - comparison with ³H-dihydromorphine and ³H-naloxone. Res.Commun.Chem.Pathol.Pharmacol. 1978 PMID: 705021
Meunier Binding of Leu⁵-enkephalin and Met⁵-enkephalin to a particulate fraction from rat cerebrum. FEBS Lett. 1977 PMID: 862920
DiMaio Synthesis and pharmacological characterization in vitro of cyclic enkephalin analogues: effect of conformational constraints on opiate receptor selectivity. J.Med.Chem. 1982 PMID: 6296388

[Leu⁵]-Enkephalin

Tocris Bioscience, part of Bio-Techne | Catalog # 1889

Key Product Details

Biological Activity for [Leu⁵]-Enkephalin

Technical Data for [Leu⁵]-Enkephalin

Solubility for [Leu⁵]-Enkephalin

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for [Leu⁵]-Enkephalin

Product Documents for [Leu⁵]-Enkephalin

COA

Certificate of Analysis

SDS

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[Leu5]-Enkephalin

Tocris Bioscience, part of Bio-Techne | Catalog # 1889

Key Product Details

Biological Activity for [Leu5]-Enkephalin

Technical Data for [Leu5]-Enkephalin

Solubility for [Leu5]-Enkephalin

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for [Leu5]-Enkephalin

Product Documents for [Leu5]-Enkephalin

COA

Certificate of Analysis

SDS

[Leu⁵]-Enkephalin

Biological Activity for [Leu⁵]-Enkephalin

Technical Data for [Leu⁵]-Enkephalin

Solubility for [Leu⁵]-Enkephalin

References for [Leu⁵]-Enkephalin

Product Documents for [Leu⁵]-Enkephalin