Motilin (human, porcine)

Name: Motilin (human, porcine)
Brand: Tocris Bioscience
SKU: 2264
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 2264

(1)

Citations (1)

COA / SDS

Endogenous peptide regulator of gastrointestinal motility

Key Product Details

Description:	Endogenous peptide regulator of gastrointestinal motility
Purity:	≥95% (HPLC)
Molecular Weight:	2699.07

View Full Technical Details for Motilin (human, porcine)

Technical Data
Citations / Reviews (1)

Biological Activity for Motilin (human, porcine)

Motilin (human, porcine) is an endogenous motilin receptor ligand (K_i = 2.3 nM) that regulates gastrointestinal motor function. Stimulates contraction of gut smooth muscle (EC₅₀ = 1 nM) and increases pepsin release.

Technical Data for Motilin (human, porcine)

M. Wt	2699.07
Formula	C₁₂₀H₁₈₈N₃₄O₃₅S
Single Letter Sequence	FVPIFTYGELQRMQEKERNKGQ
Storage	Store at -20°C
Purity	≥95% (HPLC)
CAS Number	52906-92-0
PubChem ID	16136567
InChi Key	LVRVABPNVHYXRT-BQWXUCBYSA-N
Smiles	[H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Motilin (human, porcine)

Solubility

Soluble to 1mg/ml in water

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References for Motilin (human, porcine)

References are publications that support the biological activity of the product.

Coulie Identification of peptide ligand-binding domains within the human motilin receptor using photoaffinity labeling. J.Biol.Chem. 2001 PMID: 11461914
Huang Signaling pathways mediating gastrointestinal smooth muscle contraction and MLC20 phosphorylation by motilin receptors. Am.J.Physiol.Gastrointest.Liver Physiol. 2005 PMID: 15591586
Itoh Motilin and clinical application. Peptides 1997 PMID: 9210180