P7C3

Name: P7C3
Brand: Tocris Bioscience
SKU: 4076

Tocris Bioscience, part of Bio-Techne | Catalog # 4076

Citations (5)

COA / SDS

NAMPT activator; also proneurogenic and neuroprotective

Key Product Details

Chemical Name:	3,6-Dibromo-α-[(phenylamino)methyl]-9H-carbazole-9-ethanol
Purity:	≥99%

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Technical Data
Citations

Biological Activity for P7C3

P7C3 is a NAMPT activator. Proneurogenic and neuroprotective. Protects newborn neurons in the dentate gyrus by mitigating cell death. Also enhances learning and memory in aged rats. Orally available and brain penetrant. Also revents doxorubicin-mediated toxicity in osteosarcoma cells and restores intracellular NAD levels.

Technical Data for P7C3

Formula	C₂₁H₁₈Br₂N₂O
Storage	Store at RT
Purity	≥99%
CAS Number	301353-96-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for P7C3

Solubility

Soluble Soluble to 100 mM in DMSO

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References for P7C3

References are publications that support the biological activity of the product.

Wang et al. P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage. Cell, 2014;158:1324 PMID: 25215490
Pieper et al. Discovery of a proneurogenic, neuroprotective chemical. Cell, 2010;142:39 PMID: 20603013

P7C3

Tocris Bioscience, part of Bio-Techne | Catalog # 4076

Key Product Details

Biological Activity for P7C3

Technical Data for P7C3

Solubility for P7C3

Dilution Calculator

Reconstitution Calculator

References for P7C3

Product Documents for P7C3

COA

Certificate of Analysis

SDS

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