Perhexiline maleate

Name: Perhexiline maleate
Brand: Tocris Bioscience
SKU: 5166
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 5166

(1)

Citations (2)

COA / SDS

Carnitine palmitoyltransferase 1 and 2 (CPT1/2) inhibitor

Key Product Details

Description:	Carnitine palmitoyltransferase 1 and 2 (CPT1/2) inhibitor
Chemical Name:	2-(2,2-Dicyclohexylethyl)piperidine maleate
Purity:	≥99% (HPLC)
Molecular Weight:	393.56

View Full Technical Details for Perhexiline maleate

Technical Data
Citations / Reviews (1)

Biological Activity for Perhexiline maleate

Perhexiline maleate is a carnitine palmitoyltransferase 1 and 2 (CPT1/2) inhibitor. Inhibits palmitate oxidation in rat cardiomyocytes and increases cardiac efficiency in isolated rat hearts. Antianginal.

Compound Libraries for Perhexiline maleate

Perhexiline maleate is also offered as part of the Tocriscreen 2.0 Max. Find out more about compound libraries available from Tocris.

Technical Data for Perhexiline maleate

M. Wt	393.56
Formula	C₁₉H₃₅N.C₄H₄O₄
Storage	Store at +4°C
Purity	≥99% (HPLC)
CAS Number	6724-53-4
PubChem ID	5284439
InChi Key	JDZOTSLZMQDFLG-BTJKTKAUSA-N
Smiles	OC(\C=C/C(O)=O)=O.C1(CC(C3CCCCC3)C2CCCCC2)NCCCC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Perhexiline maleate

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	39.36	100
	ethanol	7.87	20

Preparing Stock Solutions for Perhexiline maleate

The following data is based on the product molecular weight 393.56.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.54 mL	12.70 mL	25.41 mL
5 mM	0.51 mL	2.54 mL	5.08 mL
10 mM	0.25 mL	1.27 mL	2.54 mL
50 mM	0.05 mL	0.25 mL	0.51 mL

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Reconstitution Calculator

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References for Perhexiline maleate

References are publications that support the biological activity of the product.

Unger Dissociation between metabolic and efficiency effects of perhexiline in normoxic rat myocardium. J.Cardiovasc.Pharmacol. 2005 PMID: 16306812
Yin Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome. J.Mol.Cell.Cardiol. 2013 PMID: 23277191
Kennedy Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiod. Biochem.Pharmacol. 1996 PMID: 8694852