PF 429242 dihydrochloride

Biological Activity for PF 429242 dihydrochloride

Technical Data for PF 429242 dihydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for PF 429242 dihydrochloride

References for PF 429242 dihydrochloride

References are publications that support the biological activity of the product.

• Hay et al. Aminopyrrolidineamide inhibitors of site-1 protease. Bioorg.Med.Chem.Lett., 2007;17:4411 PMID: 17583500
• Hawkins et al. Pharmacologic inhibition of site 1 protease activity inhibits sterol regulatory element-binding protein processing and reduces lipogenic enzyme gene expression and lipid synthesis in cultured cells and experimental animals. J.Pharmacol.Exp.Ther., 2008;326:801 PMID: 18577702
• Urata et al. Antiviral activity of a small-molecule inhibitor of arenavirus glycoprotein processing by the cellular site 1 protease. J.Virol., 2011;85:795 PMID: 21068251
• Olmstead Human subtilase SKI-1/S1P is a master regulator of the HCV lifecycle and a potential host cell target for developing indirect-acting antiviral agents. PLoS.Pathog., 2012;8:e1002468 PMID: 22241994