(+)-Abscisic Acid

Name: (+)-Abscisic Acid
Brand: Tocris Bioscience
SKU: 6554

Tocris Bioscience, part of Bio-Techne | Catalog # 6554

COA / SDS

Endogenous LANCL2 agonist

Discontinued Product

6554 has been discontinued. View all Other Synthase/Synthetase Compounds products.

Key Product Details

Description:	Endogenous LANCL2 agonist
Chemical Name:	(2Z,4E)-5-[(1S)-1-Hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl]-3-methyl-2,4-pentadienoic acid
Purity:	≥98% (HPLC)
Molecular Weight:	264.32

View Full Technical Details for (+)-Abscisic Acid

Technical Data
Citations

Biological Activity for (+)-Abscisic Acid

(+)-Abscisic Acid is an endogenous lanthionine synthetase C-like 2 (LANCL2) ligand. Stimulates glucose uptake by myocytes and pre-adipocytes in vitro, and by brown adipose tissue in vivo. Acts as a pro-inflammatory modulator of innate immune system cells. Stimulates proliferation of human mesenchymal and hematopoietic stem cells. Also used to control Cas9 via a RNA polymerase-based biosensor.

Technical Data for (+)-Abscisic Acid

M. Wt	264.32
Formula	C₁₅H₂₀O₄
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	21293-29-8
PubChem ID	5280896
InChi Key	JLIDBLDQVAYHNE-YKALOCIXSA-N
Smiles	CC(/C=C/[C@]1(C(C)=CC(CC1(C)C)=O)O)=C/C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for (+)-Abscisic Acid

References are publications that support the biological activity of the product.

Pu Multidimensional control of Cas9 by evolved RNA polymerase-based biosensors. ACS Chem.Biol. 2018 PMID: 28809467
Fresia G-protein coupling and nuclear translocation of the human abscisic acid receptor LANCL2. Sci.Rep. 2016 PMID: 27222287
Sturla Abscisic acid enhances glucose disposal and induces brown fat activity in adipocytes in vitro and in vivo. Biochim.Biophys.Acta. 2017 PMID: 27871880
Carbo An N,N-Bis(benzimidazolylpicolinoyl)piperazine (BT-11): A novel lanthionine synthetase C-Like 2-based therapeutic for inflammatory bowel disease. J.Med.Chem. 2016 PMID: 27933891

(+)-Abscisic Acid

Tocris Bioscience, part of Bio-Techne | Catalog # 6554

Key Product Details

Biological Activity for (+)-Abscisic Acid

Technical Data for (+)-Abscisic Acid

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for (+)-Abscisic Acid

Product Documents for (+)-Abscisic Acid

COA

Certificate of Analysis

SDS

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