PSB 1114

Name: PSB 1114
Brand: Tocris Bioscience
SKU: 4333

Tocris Bioscience, part of Bio-Techne | Catalog # 4333

Citations (8)

COA / SDS

Potent, selective P2Y2 agonist

Key Product Details

Description:	Potent, selective P2Y₂ agonist
Chemical Name:	4-Thiouridine-5'-O-(β,γ-difluoromethylene)triphosphate tetrasodium salt
Purity:	≥98% (HPLC)
Molecular Weight:	622.14

View Full Technical Details for PSB 1114

Technical Data
Citations

Biological Activity for PSB 1114

PSB 1114 is a potent, selective P2Y₂ agonist (EC₅₀ = 0.134 μM). Displays >60-fold selectivity versus P2Y₄ and P2Y₆ receptors.

Technical Data for PSB 1114

M. Wt	622.14
Formula	C₁₀H₁₁F₂N₂Na₄O₁₃P₃S
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	1657025-60-9
PubChem ID	90488930
InChi Key	KATPYMNMKKBLAH-GENVZAMMSA-J
Smiles	[Na+].[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)C(O[C@@H]1COP([O-])(=O)OP([O-])(=O)C(F)(F)P([O-])([O-])=O)N1C=CC(=S)NC1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for PSB 1114

Solubility

Soluble in water (supplied pre-dissolved at a concentration of 10mM)

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References for PSB 1114

References are publications that support the biological activity of the product.

El-Tayeb Structural modifications of UMP, UDP, and UTP leading to subtype-selective agonists for P2Y₂, P2Y₄, and P2Y₆ receptors. J.Med.Chem. 2011 PMID: 21417463