(RS)-2-Hydroxyglutaric acid disodium salt

Name: ( RS )-2-Hydroxyglutaric acid disodium salt
Brand: Tocris Bioscience
SKU: 6122

Tocris Bioscience, part of Bio-Techne | Catalog # 6122

COA / SDS

Metabolite

Key Product Details

Description:	Metabolite
Chemical Name:	(RS)-2-Hydroxypentanedioic acid disodium salt
Molecular Weight:	192.08

View Full Technical Details for (RS)-2-Hydroxyglutaric acid disodium salt

Technical Data
Citations

Biological Activity for (RS)-2-Hydroxyglutaric acid disodium salt

(RS)-2-Hydroxyglutaric acid disodium salt is an oncometabolite with R- and S- enantiomers overproduced in the neurometabolic disease 2-hydroxyglutaric aciduria (2-HGA).

Technical Data for (RS)-2-Hydroxyglutaric acid disodium salt

M. Wt	192.08
Formula	C₅H₆Na₂O₅
Storage	Store at -20°C
CAS Number	40951-21-1
PubChem ID	134081824
InChi Key	DZHFTEDSQFPDPP-UHFFFAOYSA-L
Smiles	OC(C(O[Na])=O)CCC(O[Na])=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for (RS)-2-Hydroxyglutaric acid disodium salt

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	19.21	100

Preparing Stock Solutions for (RS)-2-Hydroxyglutaric acid disodium salt

The following data is based on the product molecular weight 192.08.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	5.21 mL	26.03 mL	52.06 mL
5 mM	1.04 mL	5.21 mL	10.41 mL
10 mM	0.52 mL	2.60 mL	5.21 mL
50 mM	0.10 mL	0.52 mL	1.04 mL

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Reconstitution Calculator

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References for (RS)-2-Hydroxyglutaric acid disodium salt

References are publications that support the biological activity of the product.

Du and Hu The roles of 2-Hydroxyglutarate. Front.Cell Dev.Biol. 2021 PMID: 33842477