(RS)-AMPA

Name: ( RS )-AMPA
Brand: Tocris Bioscience
SKU: 0169
Rating: 5 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 0169

(1)

Citations (27)

COA / SDS

Selective AMPA agonist

Key Product Details

Description:	Selective AMPA agonist
Chemical Name:	(RS)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
Purity:	≥99% (HPLC)
Molecular Weight:	186.17

View Full Technical Details for (RS)-AMPA

Technical Data
Citations / Reviews (1)

Biological Activity for (RS)-AMPA

(RS)-AMPA is a prototypical and defining agonist for the AMPA subgroup of ionotropic glutamate receptors.

Active Enantiomer, Inactive Enantiomer and Hydrobromide Salt also available.

Technical Data for (RS)-AMPA

M. Wt	186.17
Formula	C₇H₁₀N₂O₄
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	77521-29-0
PubChem ID	1221
InChi Key	UUDAMDVQRQNNHZ-UHFFFAOYSA-N
Smiles	CC1=C(CC(N)C(O)=O)C(O)=NO1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for (RS)-AMPA

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	1.86	10 with gentle warming

Preparing Stock Solutions for (RS)-AMPA

The following data is based on the product molecular weight 186.17.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	53.71 mL	268.57 mL	537.14 mL
0.5 mM	10.74 mL	53.71 mL	107.43 mL
1 mM	5.37 mL	26.86 mL	53.71 mL
5 mM	1.07 mL	5.37 mL	10.74 mL

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Reconstitution Calculator

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References for (RS)-AMPA

References are publications that support the biological activity of the product.

Krogsgaard-Larsen New class of glutamate agonist structurally related to ibotenic acid. Nature 1980 PMID: 6101908
Honore The binding of ³H-AMPA, a structural analogue of glutamic acid, to rat brain membranes. J.Neurochem. 1982 PMID: 6125564