SB 205607 dihydrobromide

Name: SB 205607 dihydrobromide
Brand: Tocris Bioscience
SKU: 0921

Tocris Bioscience, part of Bio-Techne | Catalog # 0921

Citations (3)

COA / SDS

Selective, high affinity non-peptide δ1 agonist

Key Product Details

Chemical Name:	(R,S)-(±)-2-Methyl-4aa-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12aa-octahydroquinolino[2,3,3-g]isoquinoline dihydrobromide
Purity:	≥97%
Molecular Weight:	506.28 kDa

View Full Technical Details for SB 205607 dihydrobromide

Technical Data
Citations

Biological Activity for SB 205607 dihydrobromide

The first described non-peptide δ₁ opioid receptor agonist with very high affinity and selectivity for the δ₁ subtype (K_i values are 1.12, 2320 and 1790 nM at δ₁, μ and κ receptors respectively).

Technical Data for SB 205607 dihydrobromide

M. Wt	506.28 kDa
Formula	C₂₃H₂₄N₂O.2HBr
Storage	Store at RT
Purity	≥97%
CAS Number	1217628-73-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for SB 205607 dihydrobromide

Solubility

Soluble Soluble to 100 mM in water and to 100 mM in DMSO

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References for SB 205607 dihydrobromide

References are publications that support the biological activity of the product.

Kamei et al. Antinociceptive effects of the selective non-peptidic δ-opioid receptor agonist TAN-67 in diabetic mice. Eur.J.Pharmacol., 1995;276:131 PMID: 7781682
Nagase et al. The pharmacological profile of δ opioid receptor ligands (+) and (-) TAN-67 on pain modulation. Life Sci., 2001;68:2227 PMID: 11358331
Knap et al. Properties of TAN-67, a non-peptidic β-opioid receptor agonist, at cloned human δ- and μ-opioid receptors. Eur.J.Pharmacol., 1995;291:129 PMID: 8566162
Nagase et al. Syntheses of non-peptidic delta opioid agonists and their structure-activity relationships. Jpn.J.Pharmacol., 1994;64:Suppl. 1, 35P