TC-P 262

Name: TC-P 262
Brand: Tocris Bioscience
SKU: 4386
Rating: 4 (1 reviews)

Tocris Bioscience, part of Bio-Techne | Catalog # 4386

(1)

Citations (1)

COA / SDS

Selective P2X3 and P2X2/3 antagonist

Discontinued Product

4386 has been discontinued. View all P2X Receptor Agonists products.

Key Product Details

Description:	Selective P2X₃ and P2X_2/3 antagonist
Chemical Name:	5-[5-Methyl-2-(1-methylethyl)phenoxy]-2,4-pyrimidinediamine
Purity:	≥99% (HPLC)
Molecular Weight:	258.32

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Technical Data
Citations / Reviews (1)

Biological Activity for TC-P 262

TC-P 262 is a selective P2X₃ and P2X_2/3 receptor antagonist (pIC₅₀ values are 7.39 and 6.68 respectively). Displays no detectable activity at P2X₁, P2X₂, P2X₄ and P2X₇ receptors (pIC₅₀ < 4.7).

Technical Data for TC-P 262

M. Wt	258.32
Formula	C₁₄H₁₈N₄O
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	873398-67-5
PubChem ID	59598765
InChi Key	RAKSAPLZNJXYRB-UHFFFAOYSA-N
Smiles	NC1=NC(N)=NC=C1OC2=C(C(C)C)C=CC(C)=C2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for TC-P 262

References are publications that support the biological activity of the product.

Ballini Characterization of three diaminopyrimidines as potent and selective antagonists of P2X₃ and P2X_2/3 receptors with in vivo efficacy in a pain model. Br.J.Pharmacol. 2011 PMID: 21410458

TC-P 262

Tocris Bioscience, part of Bio-Techne | Catalog # 4386

Key Product Details

Biological Activity for TC-P 262

Technical Data for TC-P 262

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for TC-P 262

Product Documents for TC-P 262

COA

Certificate of Analysis

SDS

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