UBP 301

Name: UBP 301
Brand: Tocris Bioscience
SKU: 1766

Tocris Bioscience, part of Bio-Techne | Catalog # 1766

Citations (11)

COA / SDS

Kainate antagonist

Key Product Details

Description:	Kainate antagonist
Chemical Name:	(αS)-α-Amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-5-iodo-2,4-dioxo-1(2H)-pyrimidinepropanoic acid
Purity:	≥98% (HPLC)
Molecular Weight:	459.2

View Full Technical Details for UBP 301

Technical Data
Citations

Biological Activity for UBP 301

UBP 301 is a potent kainate receptor antagonist (apparent K_d = 5.94 μM). Displays ~ 30-fold selectivity over AMPA receptors.

Technical Data for UBP 301

M. Wt	459.2
Formula	C₁₅H₁₄IN₃O₆
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	569371-10-4
PubChem ID	6604913
InChi Key	JHSYCOCOIYSZGI-NSHDSACASA-N
Smiles	O=C(C(I)=CN1C[C@H](N)C(O)=O)N(CC2=CC=C(C(O)=O)C=C2)C1=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for UBP 301

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	2.3	5 with gentle warming

Preparing Stock Solutions for UBP 301

The following data is based on the product molecular weight 459.2.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.05 mM	43.55 mL	217.77 mL	435.54 mL
0.25 mM	8.71 mL	43.55 mL	87.11 mL
0.5 mM	4.36 mL	21.78 mL	43.55 mL
2.5 mM	0.87 mL	4.36 mL	8.71 mL

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Reconstitution Calculator

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References for UBP 301

References are publications that support the biological activity of the product.

More Structural requirements for novel willardiine derivatives acting as AMPA and kainate receptor antagonists. Br.J.Pharmacol. 2003 PMID: 12684265