VU 0155041

Name: VU 0155041
Brand: Tocris Bioscience
SKU: 3248

Tocris Bioscience, part of Bio-Techne | Catalog # 3248

Citations (3)

COA / SDS

Potent positive allosteric modulator of mGlu4 receptors

Discontinued Product

3248 has been discontinued. View all Group III mGluR Agonists products.

Key Product Details

Description:	Potent positive allosteric modulator of mGlu₄ receptors
Chemical Name:	cis-2-[[(3,5-Dichlorophenyl)amino]carbonyl]cyclohexanecarboxylic acid
Purity:	≥99% (HPLC)
Molecular Weight:	316.18

View Full Technical Details for VU 0155041

Technical Data
Citations

Biological Activity for VU 0155041

VU 0155041 is a potent, positive allosteric modulator/allosteric agonist at mGlu₄ receptors (EC₅₀ = 798 and 693 nM at human and rat mGlu₄ receptors respectively). Active in in vivo models of Parkinson's disease following i.c.v. administration. Also available as sodium salt (Cat. No. 3311).

Technical Data for VU 0155041

M. Wt	316.18
Formula	C₁₄H₁₅Cl₂NO₃
Storage	Store at RT
Purity	≥99% (HPLC)
CAS Number	1093757-42-6
PubChem ID	90488819
InChi Key	QYHQKAPECWRTME-FBVLPHPLSA-N
Smiles	O=[C@](NC2=CC(Cl)=CC(Cl)=C2)[C@H]1CCCC[C@H]1[C@@](O)=O.O=[C@](NC4=CC(Cl)=CC(Cl)=C4)[C@@H]3CCCC[C@@H]3C(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for VU 0155041

References are publications that support the biological activity of the product.

Niswender Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4. Mol.Pharmacol. 2008 PMID: 18664603

VU 0155041

Tocris Bioscience, part of Bio-Techne | Catalog # 3248

Key Product Details

Biological Activity for VU 0155041

Technical Data for VU 0155041

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for VU 0155041

Product Documents for VU 0155041

COA

Certificate of Analysis

SDS

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