VUF 11222

Name: VUF 11222
Brand: Tocris Bioscience
SKU: 5668

Tocris Bioscience, part of Bio-Techne | Catalog # 5668

Citations (3)

COA / SDS

High affinity non-peptide CXCR3 agonist

Key Product Details

Description:	High affinity non-peptide CXCR3 agonist
Chemical Name:	2'-Bromo-N-[[(1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl]methyl]-N,N-dimethyl-[1,1'-biphenyl]-4-methanaminium iodide
Purity:	≥98% (HPLC)
Molecular Weight:	552.33

View Full Technical Details for VUF 11222

Technical Data
Citations

Biological Activity for VUF 11222

VUF 11222 is a high affinity non-peptide CXCR3 agonist (pK_i = 7.2).

Technical Data for VUF 11222

M. Wt	552.33
Formula	C₂₅H₃₁BrIN
Storage	Store at -20°C
Purity	≥98% (HPLC)
CAS Number	1414376-84-3
PubChem ID	71459294
InChi Key	IXXWHYDKYNWDKJ-IUQUCOCYSA-M
Smiles	C[N+](CC1=CC=C(C2=CC=CC=C2Br)C=C1)(C)CC3=CC[C@H]4C[C@@H]3C(C)4C.[I-]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for VUF 11222

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	55.23	100
	ethanol	5.52	10 with gentle warming

Preparing Stock Solutions for VUF 11222

The following data is based on the product molecular weight 552.33.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.81 mL	9.05 mL	18.11 mL
5 mM	0.36 mL	1.81 mL	3.62 mL
10 mM	0.18 mL	0.91 mL	1.81 mL
50 mM	0.04 mL	0.18 mL	0.36 mL

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References for VUF 11222

References are publications that support the biological activity of the product.

Wijtmans Chemical subtleties in small-molecule modulation of peptide receptor function: the case of CXCR3 biaryl-type ligands. J.Med.Chem. 2012 PMID: 23150943