BzF

Name: BzF
Brand: Tocris Bioscience
SKU: 6786

Tocris Bioscience, part of Bio-Techne | Catalog # 6786

COA / SDS

Photoreactive unnatural amino acid; photo-crosslinker

Discontinued Product

6786 has been discontinued. View all Photoactivatable Cross-linking Probes products.

Key Product Details

Description:	Photoreactive unnatural amino acid; photo-crosslinker
Chemical Name:	4-Benzoyl-L-phenylalanine
Purity:	≥98% (HPLC)
Molecular Weight:	269.3

View Full Technical Details for BzF

Technical Data
Citations

Biological Activity for BzF

BzF is a photoreactive unnatural amino acid. Acts as photo cross-linking probe when incorporated into proteins, including ion channels, transporters and GPCRs. When exposed to UV light it forms a covalent cross-link with a C-H bond-containing group, enabling selective and potent UV-driven photoinactivation of protein function. Has been used to study protein-protein and protein-ligand interactions.

Technical Data for BzF

M. Wt	269.3
Formula	C₁₆H₁₅NO₃
Storage	Store at +4°C
Purity	≥98% (HPLC)
CAS Number	104504-45-2
PubChem ID	7020128
InChi Key	TVIDEEHSOPHZBR-AWEZNQCLSA-N
Smiles	N[C@H](C(O)=O)CC1=CC=C(C(C2=CC=CC=C2)=O)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

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References for BzF

References are publications that support the biological activity of the product.

Klippenstein Probing ion channel structure and function using light-sensitive amino acids. Trends Biochem.Sci. 2018 PMID: 29650383
Klippenstein Photoinactivation of glutamate receptors by genetically encoded unnatural amino acids. J.Neurosci. 2014 PMID: 24431456
Ye Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis. J.Biol.Chem. 2008 PMID: 17993461

BzF

Tocris Bioscience, part of Bio-Techne | Catalog # 6786

Key Product Details

Biological Activity for BzF

Technical Data for BzF

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

References for BzF

Product Documents for BzF

COA

Certificate of Analysis

SDS

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