Disulfide biotin azide

Name: Disulfide biotin azide
Brand: Tocris Bioscience
SKU: 7768

Tocris Bioscience, part of Bio-Techne | Catalog # 7768

COA / SDS

Azide-activated biotinylation reagent; labels alkyne moieties via copper-catalyzed click chemistry

Key Product Details

Description:	Azide-activated biotinylation reagent; labels alkyne moieties via copper-catalyzed click chemistry
Chemical Name:	N-(24-Azido-12,20-dioxo-3,6,9-trioxa-16,17-dithia-13,21-diazatetracosyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
Purity:	≥90% (HPLC)
Molecular Weight:	692.91

View Full Technical Details for Disulfide biotin azide

Technical Data
Citations

Biological Activity for Disulfide biotin azide

Disulfide Biotin Azide is an azide-activated cleavable (disulphide) biotin probe. It allows the biotinylation of molecules containing alkyne moiety via copper-catalyzed click chemistry reactions.

Technical Data for Disulfide biotin azide

M. Wt	692.91
Formula	C₂₇H₄₈N₈O₇S₃
Storage	Store at -20°C
Purity	≥90% (HPLC)
CAS Number	2866429-93-6
PubChem ID	102514779
InChi Key	FVMIKTRZXCSAEY-MCEYFSPLSA-N
Smiles	O=C(N1)N[C@]([C@]1([H])CS2)([H])[C@@H]2CCCCC(NCCOCCOCCOCCC(NCCSSCCC(NCCCN=[N+]=[N-])=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Disulfide biotin azide

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	DMSO	13.86	20

Preparing Stock Solutions for Disulfide biotin azide

The following data is based on the product molecular weight 692.91.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.2 mM	7.22 mL	36.08 mL	72.16 mL
1 mM	1.44 mL	7.22 mL	14.43 mL
2 mM	0.72 mL	3.61 mL	7.22 mL
10 mM	0.14 mL	0.72 mL	1.44 mL

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References for Disulfide biotin azide

References are publications that support the biological activity of the product.

Chen Design, optimization, and study of small molecules that target Tau pre-mRNA and affect splicing. J.Am.Chem.Soc. 2020 PMID: 32364710
Eisen MicroRNAs cause accelerated decay of short-tailed target mRNAs. Mol.Cell 2020 PMID: 31902668