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Table of Contents:

Introduction

Rather than just meeting industry standards, we’re on a mission to define them. We’ve modernized our methods of cell culture and protein purification to safeguard your access to high-quality recombinant proteins throughout your research journey. Our next generation of cytokines and growth factors merges the renowned quality of R&D Systems™ with Bio-Techne innovation, offering you an unparalleled combination of dependability and stability of supply. These best-in-class proteins ensure your research remains at the forefront of progress.

Benefits for Your Research

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Increased Supply

Increased manufacturing capacity and yield for supply at all stages of your research 

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Supply Chain Reliability

Investments in our process aim for an uninterrupted supply

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Time & Cost-Savings

Cost-effective proteins with larger lot sizes, allowing for less time spent on bridging studies

Our Uncompromising Protein Quality

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Equivalent Bioactivity

Bioactivities remain equivalent to our legacy proteins, making your transition easier

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High Lot-to-Lot Consistency

Each new lot tested side-by-side with previous lots to guarantee a reliable product

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High Purity and Low Endotoxin Levels

Over 95% purity with an industry-leading low endotoxin level

Next Generation Proteins

Recombinant Protein

Legacy Product

Expression System

Next Generation Products

Side-by-Side Comparisons 

IL-2 202-IL E. coli BT-002 Data
IL-4 204-IL E. coli BT-004 Data
IL-7 207-IL E. coli BT-007 Data
IL-15 247-ILB E. coli BT-015 Data
SCF 255-SC E. coli BT-SCF Data
VEGF 10318-VE E. coli BT-VEGF Data
Betacellulin 261-CE E. coli BT-BTC Data
FGF basic/FGF2 233-FB E. coli 3718-FB Data
233-FB E. coli BT-FGFB Data
BDNF 248-BDB Sf21 vs. CHO 11166-BD Data
248-BDB Sf21 vs. E. coli BT-BDNF Data
TGF-beta 1 240-B CHO vs. HEK293 7754-BH Data
240-B CHO 11409-BH Data
TGF-beta 3 243-B3 Sf21 vs. CHO 8420-B3 Data
Flt-3 ligand 308-FK Sf21 vs. HEK293 308-FKHB Data
308-FKE E. coli BT-FT3L Data
IL-11 218-IL Sf21 vs. CHO 10836-IL Data
IL-12 219-IL CHO vs. HEK293 10018-IL Data
IL-23 1290-IL HEK293 vs. CHO 11349-IL Data
CD40L 6420-CL HEK293 6420-CLB Data
Thrombopoietin 288-TP Sf21 vs. HEK293 288-TPH Data
Activin A 338-AC CHO 11348-AC Data

Find our next generation proteins in the unit conversion table here
While the conversion unit table provides an approximation for conversion units, each of our GMP and Animal-Free proteins have lot-specific values on their CoAs.

Comparison of Legacy to Next Generation Proteins

A bioactivity graph comparing original recombinant human protein TGF-beta 1 to new Apex recombinant human protein TGF-beta 1.

Recombinant Human TGF-β1 Protein Bioactivity Comparison. The bioactivities of the legacy (240-B) and the next generation (7754-BH) Recombinant Human TGF-β1 proteins were compared by assessing their abilities to inhibit IL-4 induced cell proliferation of HT-2 mouse T cells. Based on this assay, both proteins demonstrate similar activity.

A bioactivity graph comparing original recombinant human protein IL-7 protein to new Apex recombinant human protein IL-7.

Recombinant Human IL-7 Protein Bioactivity Comparison. The legacy (207-IL) and next generation (BT-007) were measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL). Based on this assay, both proteins demonstrate similar activity.

Next Generation Protein Sample Request


Submit a request for our next generation RUO proteins while supplies lasts. Please specify your protein(s) of interest in the comment box, and a team member will reach out to confirm shipping.

Terms and Conditions: No purchase necessary. This promotion is available in the U.S., Canada, and Europe. The free sample is for the protein indicated at the top of this form and samples will be honored while supplies last. Offer void where prohibited, licensed, or restricted by federal, state, provincial, or local laws or regulation or agency/institutional policy. Other restrictions may apply.