Instrument Citation Search
At Bio-Techne, we’re changing the way scientists analyze proteins. Our innovative product portfolio helps researchers reveal new insight into proteins, advancing their understanding of protein function. As a result, our products are rapidly increasing in the scientific literature across many applications. Use this citation database to find scientific articles that feature our instruments.
Showing 1 - 60 of 60 citations
Fiter by:
Search Citations:
Instrument Platform:
Simple Western |
Articles: | |
Research Category:
Clinical Trials, Neuroscience, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Chamessian A et al.
Payne M,
View all...
Gordon I, Zhou M, Gereau R |
PMID: | 39896637 | |
Instrument Platform:
Simple Western |
Articles: | |
Research Category:
Gene Regulation, Immuno-Oncology, TPD and Induced Proximity |
Author: |
Feller F et al.
Honin I,
View all...
Miranda M, Weber H, Henze S, Hanl M, Hansen FK |
PMID: | 39804678 | |
Instrument Platform:
Simple Western |
Articles: | |
Research Category:
Metabolism, Neuroscience, Stem Cells, TPD and Induced Proximity |
Author: |
Starkie DO et al.
Arber C,
View all...
Baker T, Lightwood DJ, Wray S |
PMID: | 39665388 | |
Instrument Platform:
Simple Western |
Articles: |
(2024) Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity Nat Commun, 15 (1) :10165.
|
Research Category:
Cell Signaling, Gene Regulation, Immuno-Oncology, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Mabanglo MF et al.
Wilson B,
View all...
Noureldin M, Kimani SW, Mamai A, Krausser C, González-Álvarez H, Srivastava S, Mohammed M, Hoffer L, Chan M, Avrumutsoae J, Li ASM, Hajian T, Tucker S, Green S, Szewczyk M, Barsyte-Lovejoy D, Santhakumar V, Ackloo S, Loppnau P, Li Y, Seitova A, Kiyota T, Wang JG, Privé GG, Kuntz DA, Patel B, Rathod V, Vala A, Rout B, Aman A, Poda G, Uehling D, Ramnauth J, Halabelian L, Marcellus R, Al-Awar R, Vedadi M |
PMID: | 39580491 | |
Instrument Platform:
Simple Western |
Articles: |
(2024) Targeted protein degradation through site-specific antibody conjugation with mannose 6-phosphate glycan MAbs, 16 (1) :2415333.
|
Research Category:
Cell Signaling, Drug Discovery, Immuno-Oncology, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Mukai K et al.
Cost R,
View all...
Zhang XS, Condiff E, Cotton J, Liu X, Boudanova E, Niebel B, Piepenhagen P, Cai X, Park A, Zhou Q |
PMID: | 39434219 | |
Instrument Platform:
Simple Western |
Articles: |
(2024) Discovery of Oral Degraders of the ROS1 Fusion Protein with Potent Activity against Secondary Resistance Mutations J Med Chem, 67 (20) :18098-18123.
|
Research Category:
Cell Signaling, Immuno-Oncology, TPD and Induced Proximity |
Author: |
Peng X et al.
Guo S,
View all...
Zheng S, Hossain A, Zhang C, Mottamal M, Skripnikova E, Ma P, Martinez-Carter K, Zhang Q, Abedin F, Huckaba T, Wang G |
PMID: | 39361251 | |
Instrument Platform:
Simple Western |
Articles: | |
Research Category:
Drug Discovery, Gene Regulation, Immuno-Oncology, TPD and Induced Proximity |
Author: |
Ma M et al.
Li M,
View all...
Zhang C, Yang Z, Chen X, Lu P, Nie S, Zhang S, Ma S, Qin C |
PMID: | 39344125 | |
Instrument Platform:
Simple Western |
Articles: |
(2024) Discovery of Covalent MLKL PROTAC Degraders via Optimization of a Theophylline Derivative Ligand for Treating Necroptosis J Med Chem, 67 (17) :15353-15372.
|
Research Category:
Cell Signaling, Drug Discovery, Immuno-Oncology, Metabolism, TPD and Induced Proximity |
Author: |
Li S et al.
Ma L,
View all...
Li X, Jiang Y, Luo Z, Yin F, Zhang Y, Chen Y, Wan S, Zhou H, Kong L, Wang X |
PMID: | 39180479 | |
Instrument Platform:
Simple Western |
Articles: | |
Research Category:
Gene Regulation, Immuno-Oncology, Metabolism, TPD and Induced Proximity |
Author: |
Stokes ME et al.
Wenzl K,
View all...
Huang CC, Ortiz M, Hsu CC, Maurer MJ, Stong N, Nakayama Y, Wu L, Chiu H, Polonskaia A, Danziger SA, Towfic F, Parker J, King RL, Link BK, Slager SL, Sarangi V, Asmann YW, Novak JP, Sudhindra A, Ansell SM, Habermann TM, Hagner PR, Nowakowski GS, Cerhan JR, Novak AJ, Gandhi AK |
PMID: | 39117654 | |
Instrument Platform:
Simple Western |
Articles: |
(2024) Intrinsic signaling pathways modulate targeted protein degradation Nat Commun, 15 (1) :5379.
|
Research Category:
Apoptosis, Cell Signaling, Drug Discovery, Gene Regulation, Immuno-Oncology, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Mori Y et al.
Akizuki Y,
View all...
Honda R, Takao M, Tsuchimoto A, Hashimoto S, Iio H, Kato M, Kaiho-Soma A, Saeki Y, Hamazaki J, Murata S, Ushijima T, Hattori N, Ohtake F |
PMID: | 38956052 | |
Instrument Platform:
Simple Western |
Articles: |
(2024) Discovery of Monovalent Direct Degraders of BRD4 That Act Via the Recruitment of DCAF11 Mol Cancer Ther.
|
Research Category:
Drug Discovery, Immuno-Oncology, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Parker GS et al.
Toth JI,
View all...
Fish S, Blanco GA, Kampert T, Li X, Yang L, Stumpf CR, Steadman K, Jamborcic A, Chien S, Daniele E, Dearie A, Leriche G, Bailey S, Thompson PA |
PMID: | 38907538 | |
Instrument Platform:
Simple Western |
Articles: |
(2024) A molecular glue RBM39-degrader induces synthetic lethality in cancer cells with homologous recombination repair deficiency NPJ Precis Oncol, 8 (1) :117.
|
Research Category:
Biomarkers, Immuno-Oncology, TPD and Induced Proximity |
Author: |
Kohsaka S et al.
Yagishita S,
View all...
Shirai Y, Matsuno Y, Ueno T, Kojima S, Ikeuchi H, Ikegami M, Kitada R, Yoshioka KI, Toshimitsu K, Tabata K, Yokoi A, Doi T, Yamamoto N, Owa T, Hamada A, Mano H |
PMID: | 38789724 | |
Instrument Platform:
Simple Western |
Articles: | |
Research Category:
Clinical Trials, Gene Regulation, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Giardina SF et al.
Valdambrini E,
View all...
Singh PK, Bacolod MD, Babu-Karunakaran G, Peel M, Warren JD, Barany F |
PMID: | 38554135 | |
Instrument Platform:
Simple Western |
Articles: |
(2024) Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria Nat Commun, 15 (1) :2005.
|
Research Category:
Drug Discovery, TPD and Induced Proximity |
Author: |
Junk L et al.
Schmiedel VM,
View all...
Guha S, Fischel K, Greb P, Vill K, Krisilia V, van Geelen L, Rumpel K, Kaur P, Krishnamurthy RV, Narayanan S, Shandil RK, Singh M, Kofink C, Mantoulidis A, Biber P, Gmaschitz G, Kazmaier U, Meinhart A, Leodolter J, Hoi D, Junker S, Morreale FE, Clausen T, Kalscheuer R, Weinstabl H, Boehmelt G |
PMID: | 38443338 | |
Instrument Platform:
Simple Western |
Articles: |
(2024) DCAF1-based PROTACs with activity against clinically validated targets overcoming intrinsic- and acquired-degrader resistance Nat Commun, 15 (1) :275.
|
Research Category:
Cell Signaling, Drug Discovery, Gene Regulation, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Schröder M et al.
Renatus M,
View all...
Liang X, Meili F, Zoller T, Ferrand S, Gauter F, Li X, Sigoillot F, Gleim S, Stachyra TM, Thomas JR, Begue D, Khoshouei M, Lefeuvre P, Andraos-Rey R, Chung B, Ma R, Pinch B, Hofmann A, Schirle M, Schmiedeberg N, Imbach P, Gorses D, Calkins K, Bauer-Probst B, Maschlej M, Niederst M, Maher R, Henault M, Alford J, Ahrne E, Tordella L, Hollingworth G, Thomä NH, Vulpetti A, Radimerski T, Holzer P, Carbonneau S, Thoma CR |
PMID: | 38177131 | |
Instrument Platform:
Simple Western |
Articles: |
(2024) Palazestrant (OP-1250), A Complete Estrogen Receptor Antagonist, Inhibits Wild-type and Mutant ER-positive Breast Cancer Models as Monotherapy and in Combination Mol Cancer Ther, 23 (3) :285-300.
|
Research Category:
Cell Signaling, Immuno-Oncology, Metabolism, Neuroscience, TPD and Induced Proximity |
Author: |
Parisian AD et al.
Barratt SA,
View all...
Hodges-Gallagher L, Ortega FE, Peña G, Sapugay J, Robello B, Sun R, Kulp D, Palanisamy GS, Myles DC, Kushner PJ, Harmon CL |
PMID: | 38102750 | |
Instrument Platform:
Simple Western |
Articles: |
(2023) PROTACs Targeting MLKL Protect Cells from Necroptosis J Med Chem, 66 (16) :11216-11236.
|
Research Category:
Apoptosis, Cell Signaling, Metabolism, TPD and Induced Proximity |
Author: |
Rathje OH et al.
Perryman L,
View all...
Payne RJ, Hamprecht DW |
PMID: | 37535857 | |
Instrument Platform:
Simple Western |
Articles: |
(2023) Development of the first geldanamycin-based HSP90 degraders Front Chem, 11:1219883.
|
Research Category:
Cell Signaling, Immuno-Oncology, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Wurnig S et al.
Vogt M,
View all...
Hogenkamp J, Dienstbier N, Borkhardt A, Bhatia S, Hansen FK |
PMID: | 37448856 | |
Instrument Platform:
Simple Western |
Articles: |
(2023) Modeling the novel SERD elacestrant in cultured fulvestrant-refractory HR-positive breast circulating tumor cells Breast Cancer Res Treat, 201 (1) :43-56.
|
Research Category:
Cell Signaling, Clinical Trials, Immuno-Oncology, TPD and Induced Proximity |
Author: |
Dubash TD et al.
Bardia A,
View all...
Chirn B, Reeves BA, LiCausi JA, Burr R, Wittner BS, Rai S, Patel H, Bihani T, Arlt H, Bidard FC, Kaklamani VG, Aftimos P, Cortés J, Scartoni S, Fiascarelli A, Binaschi M, Habboubi N, Iafrate AJ, Toner M, Haber DA, Maheswaran S |
PMID: | 37318638 | |
Instrument Platform:
Simple Western |
Articles: |
(2023) Use of the dTAG system in vivo to degrade CDK2 and CDK5 in adult mice and explore potential safety liabilities Toxicol Sci, 194 (1) :53-69.
|
Research Category:
Bioprocess, Cell Signaling, Metabolism, Neuroscience, TPD and Induced Proximity |
Author: |
Yenerall P et al.
Sung T,
View all...
Palyada K, Qian J, Arat S, Kumpf SW, Wang SW, Biddle K, Esparza C, Chang S, Scott W, Collette W, Winrow TS, Affolter T, Shirai N, Thibault S, Wang J, Liu L, Bauchmann M, Frey J, Steyn S, Sacaan A, Vitsky A, Ahn Y, Paul T, Lum L, Oyer J, Yang A, Hu W |
PMID: | 37228089 | |
Instrument Platform:
Simple Western |
Articles: |
(2023) The BET PROTAC inhibitor dBET6 protects against retinal degeneration and inhibits the cGAS-STING in response to light damage J Neuroinflammation, 20 (1) :119.
|
Research Category:
Cell Signaling, Gene Regulation, Metabolism, Neuroscience, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Zhu X et al.
Liu W,
View all...
Tang X, Chen Y, Ge X, Ke Q, Liang X, Gan Y, Zheng Y, Zou M, Deng M, Liu Y, Li DW, Gong L |
PMID: | 37217935 | |
Instrument Platform:
Simple Western |
Articles: |
(2023) Nedd4-2 up-regulation is associated with ACE2 ubiquitination in hypertension Cardiovasc Res, 119 (11) :2130-2141.
|
Research Category:
Gene Regulation, Gene Therapy, Metabolism, Methods and Optimization, Neuroscience, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Mohammed M et al.
Ogunlade B,
View all...
Elgazzaz M, Berdasco C, Lakkappa N, Ghita I, Guidry JJ, Sriramula S, Xu J, Restivo L, Mendiola Plá MA, Bowles DE, Beyer AM, Yue X, Lazartigues E, Filipeanu CM |
PMID: | 37161607 | |
Instrument Platform:
Simple Western |
Articles: | |
Research Category:
Cell Signaling, Drug Discovery, Immuno-Oncology, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Tokarski RJ 2nd et al.
Sharpe CM,
View all...
Huntsman AC, Mize BK, Ayinde OR, Stahl EH, Lerma JR, Reed A, Carmichael B, Muthusamy N, Byrd JC, Fuchs JR |
PMID: | 37071962 | |
Instrument Platform:
Simple Western |
Articles: |
(2023) Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates Nat Commun, 14 (1) :2160.
|
Research Category:
Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Kiss L et al.
Rhinesmith T,
View all...
Luptak J, Dickson CF, Weidenhausen J, Smyly S, Yang JC, Maslen SL, Sinning I, Neuhaus D, Clift D, James LC |
PMID: | 37061529 | |
Instrument Platform:
Simple Western |
Articles: |
(2023) Discovery of Nanomolar DCAF1 Small Molecule Ligands J Med Chem, 66 (7) :5041-5060.
|
Research Category:
Immuno-Oncology, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Li ASM et al.
Kimani S,
View all...
Wilson B, Noureldin M, González-Álvarez H, Mamai A, Hoffer L, Guilinger JP, Zhang Y, von Rechenberg M, Disch JS, Mulhern CJ, Slakman BL, Cuozzo JW, Dong A, Poda G, Mohammed M, Saraon P, Mittal M, Modh P, Rathod V, Patel B, Ackloo S, Santhakumar V, Szewczyk MM, Barsyte-Lovejoy D, Arrowsmith CH, Marcellus R, Guié MA, Keefe AD, Brown PJ, Halabelian L, Al-Awar R, Vedadi M |
PMID: | 36948210 | |
Instrument Platform:
Simple Western |
Articles: |
(2023) Targeted AURKA degradation: Towards new therapeutic agents for neuroblastoma Eur J Med Chem, 247:115033.
|
Research Category:
Apoptosis, Cell Signaling, Immuno-Oncology, Metabolism, Neuroscience, TPD and Induced Proximity |
Author: |
Rishfi M et al.
Krols S,
View all...
Martens F, Bekaert SL, Sanders E, Eggermont A, De Vloed F, Goulding JR, Risseeuw M, Molenaar J, De Wilde B, Van Calenbergh S, Durinck K |
PMID: | 36549117 | |
Instrument Platform:
Simple Western |
Articles: |
(2022) Solid-Phase Synthesis of Cereblon-Recruiting Selective Histone Deacetylase 6 Degraders (HDAC6 PROTACs) with Antileukemic Activity J Med Chem, 65 (24) :16860-16878.
|
Research Category:
Apoptosis, Cell Signaling, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Sinatra L et al.
Yang J,
View all...
Schliehe-Diecks J, Dienstbier N, Vogt M, Gebing P, Bachmann LM, Sönnichsen M, Lenz T, Stühler K, Schöler A, Borkhardt A, Bhatia S, Hansen FK |
PMID: | 36473103 | |
Instrument Platform:
Simple Western |
Articles: |
(2022) Screening chimeric GAA variants in preclinical study results in hematopoietic stem cell gene therapy candidate vectors for Pompe disease Mol Ther Methods Clin Dev, 27:464-487.
|
Research Category:
Cell Signaling, Clinical Trials, Gene Therapy, Immune Cell Therapy, Neuroscience, Post-Translational Modifications, Stem Cells, TPD and Induced Proximity |
Author: |
Dogan Y et al.
Barese CN,
View all...
Schindler JW, Yoon JK, Unnisa Z, Guda S, Jacobs ME, Oborski C, Maiwald T, Clarke DL, Schambach A, Pfeifer R, Harper C, Mason C, van Til NP |
PMID: | 36419467 | |
Instrument Platform:
Simple Western |
Articles: |
(2023) cIAP1-based degraders induce degradation via branched ubiquitin architectures Nat Chem Biol, 19 (3) :311-322.
|
Research Category:
Apoptosis, Immuno-Oncology, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Akizuki Y et al.
Morita M,
View all...
Mori Y, Kaiho-Soma A, Dixit S, Endo A, Shimogawa M, Hayashi G, Naito M, Okamoto A, Tanaka K, Saeki Y, Ohtake F |
PMID: | 36316570 | |
Instrument Platform:
Simple Western |
Articles: |
(2022) A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo Nat Commun, 13 (1) :5969.
|
Research Category:
Gene Regulation, Immuno-Oncology, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Kofink C et al.
Trainor N,
View all...
Mair B, Wöhrle S, Wurm M, Mischerikow N, Roy MJ, Bader G, Greb P, Garavel G, Diers E, McLennan R, Whitworth C, Vetma V, Rumpel K, Scharnweber M, Fuchs JE, Gerstberger T, Cui Y, Gremel G, Chetta P, Hopf S, Budano N, Rinnenthal J, Gmaschitz G, Mayer M, Koegl M, Ciulli A, Weinstabl H, Farnaby W |
PMID: | 36216795 | |
Instrument Platform:
Simple Western |
Articles: |
(2022) Therapeutic and Effective CURE-PRO Molecules for E3 Ligase-Mediated Targeted Protein Degradation ACS Med Chem Lett, 13 (8) :1206-1208.
|
Research Category:
TPD and Induced Proximity |
Author: |
Kargbo RB. et al.
|
PMID: | 35978695 | |
Instrument Platform:
Simple Western |
Articles: |
(2022) BacPROTACs mediate targeted protein degradation in bacteria Cell, 185 (13) :2338-2353.e18.
|
Research Category:
Drug Discovery, Infectious Disease, Metabolism, TPD and Induced Proximity |
Author: |
Morreale FE et al.
Kleine S,
View all...
Leodolter J, Junker S, Hoi DM, Ovchinnikov S, Okun A, Kley J, Kurzbauer R, Junk L, Guha S, Podlesainski D, Kazmaier U, Boehmelt G, Weinstabl H, Rumpel K, Schmiedel VM, Hartl M, Haselbach D, Meinhart A, Kaiser M, Clausen T |
PMID: | 35662409 | |
Instrument Platform:
Simple Western |
Articles: |
(2022) Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases iScience, 25 (3) :103985.
|
Research Category:
Biomarkers, Immuno-Oncology, Monoclonal Antibodies, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Luo X et al.
Archibeque I,
View all...
Dellamaggiore K, Smither K, Homann O, Lipford JR, Mohl D |
PMID: | 35295813 | |
Instrument Platform:
Simple Western |
Articles: |
(2022) Resolving the deceptive isoform and complex selectivity of HDAC1/2 inhibitors Cell Chem Biol, 29 (7) :1140-1152.e5.
|
Research Category:
Gene Regulation, TPD and Induced Proximity |
Author: |
Payne NC et al.
Mazitschek R
View all...
|
PMID: | 35298895 | |
Instrument Platform:
Simple Western |
Articles: |
(2022) A cross-species spatiotemporal proteomic analysis identifies UBE3A-dependent signaling pathways and targets Mol Psychiatry, 27 (5) :2590-2601.
|
Research Category:
Biomarkers, Cell Signaling, Clinical Trials, Gene Regulation, Metabolism, Neuroscience, Post-Translational Modifications, Regenerative Medicine, Stem Cells, TPD and Induced Proximity |
Author: |
Pandya NJ et al.
Meier S,
View all...
Tyanova S, Terrigno M, Wang C, Punt AM, Mientjes EJ, Vautheny A, Distel B, Kremer T, Elgersma Y, Jagasia R |
PMID: | 35264729 | |
Instrument Platform:
Simple Western |
Articles: |
(2021) The CRL4DTL E3 ligase induces degradation of the DNA replication initiation factor TICRR/TRESLIN specifically during S phase Nucleic Acids Res, 49 (18) :10507-10523.
|
Research Category:
Cell Signaling, Gene Regulation, Immuno-Oncology, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Wittig KA et al.
Sansam CG,
View all...
Noble TD, Goins D, Sansam CL |
PMID: | 34534348 | |
Instrument Platform:
Simple Western |
Articles: |
(2021) Mechanistic and Structural Features of PROTAC Ternary Complexes Methods Mol Biol, 2365:79-113.
|
Research Category:
Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Casement R et al.
Bond A,
View all...
Craigon C, Ciulli A |
PMID: | 34432240 | |
Instrument Platform:
Simple Western |
Articles: |
(2021) Optimization of a Series of RIPK2 PROTACs J Med Chem, 64 (17) :12978-13003.
|
Research Category:
Apoptosis, Bioprocess, Cell Signaling, Drug Discovery, Gene Regulation, Metabolism, TPD and Induced Proximity |
Author: |
Miah AH et al.
Smith IED,
View all...
Rackham M, Mares A, Thawani AR, Nagilla R, Haile PA, Votta BJ, Gordon LJ, Watt G, Denyer J, Fisher DT, Dace P, Giffen P, Goncalves A, Churcher I, Scott-Stevens P, Harling JD |
PMID: | 34432979 | |
Instrument Platform:
Simple Western |
Articles: |
(2021) The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D Nature, 592 (7856) :794-798.
|
Research Category:
Cell Signaling, Gene Regulation, Immuno-Oncology, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Chaikovsky AC et al.
Li C,
View all...
Jeng EE, Loebell S, Lee MC, Murray CW, Cheng R, Demeter J, Swaney DL, Chen SH, Newton BW, Johnson JR, Drainas AP, Shue YT, Seoane JA, Srinivasan P, He A, Yoshida A, Hipkins SQ, McCrea E, Poltorack CD, Krogan NJ, Diehl JA, Kong C, Jackson PK, Curtis C, Petrov DA, Bassik MC, Winslow MM, Sage J |
PMID: | 33854239 | |
Instrument Platform:
Simple Western |
Articles: |
(2021) A Method for Determining the Kinetics of Small-Molecule-Induced Ubiquitination SLAS Discov, 26 (4) :547-559.
|
Research Category:
Cell Signaling, Drug Discovery, Gene Regulation, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Vieux EF et al.
Agafonov RV,
View all...
Emerson L, Isasa M, Deibler RW, Simard JR, Cocozziello D, Ladd B, Lee L, Li H, Archer S, Fitzgerald M, Michael R, Nasveschuk CG, Park ES, Kern G, Proia DA, Phillips AJ, Fisher SL |
PMID: | 33780296 | |
Instrument Platform:
Simple Western |
Articles: |
(2021) Effect of small molecule eRF3 degraders on premature termination codon readthrough Nucleic Acids Res, 49 (7) :3692-3708.
|
Research Category:
Dystrophy, Gene Regulation, Metabolism, Neuroscience, TPD and Induced Proximity |
Author: |
Baradaran-Heravi A et al.
Balgi AD,
View all...
Hosseini-Farahabadi S, Choi K, Has C, Roberge M |
PMID: | 33764477 | |
Instrument Platform:
Simple Western |
Articles: | |
Research Category:
Cell Signaling, Gene Regulation, Metabolism, TPD and Induced Proximity |
Author: |
Graham ZA et al.
DeBerry JJ,
View all...
Cardozo CP, Bamman MM |
PMID: | 33611851 | |
Instrument Platform:
Simple Western |
Articles: |
(2021) High-Throughput Quantitative Assay Technologies for Accelerating the Discovery and Optimization of Targeted Protein Degradation Therapeutics SLAS Discov, 26 (4) :503-517.
|
Research Category:
Cell Signaling, Drug Discovery, Gene Regulation, Immuno-Oncology, Metabolism, Neuroscience, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Simard JR et al.
Lee L,
View all...
Vieux E, Improgo R, Tieu T, Phillips AJ, Fisher SL, Pollock RM, Park E |
PMID: | 33430712 | |
Instrument Platform:
Simple Western |
Articles: |
(2021) Targeted degradation of the enhancer lysine acetyltransferases CBP and p300 Cell Chem Biol, 28 (4) :503-514.e12.
|
Research Category:
Gene Regulation, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Vannam R et al.
Sayilgan J,
View all...
Ojeda S, Karakyriakou B, Hu E, Kreuzer J, Morris R, Herrera Lopez XI, Rai S, Haas W, Lawrence M, Ott CJ |
PMID: | 33400925 | |
Instrument Platform:
Simple Western |
Articles: | |
Research Category:
Cell Signaling, Clinical Trials, Immuno-Oncology, TPD and Induced Proximity |
Author: |
Shomali M et al.
Cheng J,
View all...
Sun F, Koundinya M, Guo Z, Hebert AT, McManus J, Levit MN, Hoffmann D, Courjaud A, Arrebola R, Cao H, Pollard J, Lee JS, Besret L, Caron A, Bangari DS, Abecassis PY, Schio L, El-Ahmad Y, Halley F, Tabart M, Certal V, Thompson F, McCort G, Filoche-Rommé B, Cheng H, Garcia-Echeverria C, Debussche L, Bouaboula M |
PMID: | 33310762 | |
Instrument Platform:
Simple Western |
Articles: |
(2020) Quantitative expression of Ikaros, IRF4, and PSMD10 proteins predicts survival in VRD-treated patients with multiple myeloma Blood Adv, 4 (23) :6023-6033.
|
Research Category:
Biomarkers, Gene Regulation, TPD and Induced Proximity |
Author: |
Misiewicz-Krzeminska I et al.
de Ramón C,
View all...
Corchete LA, Krzeminski P, Rojas EA, Isidro I, García-Sanz R, Martínez-López J, Oriol A, Bladé J, Lahuerta JJ, San Miguel J, Rosiñol L, Mateos MV, Gutiérrez NC |
PMID: | 33284947 | |
Instrument Platform:
Simple Western |
Articles: |
(2020) Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2 Commun Biol, 3 (1) :140.
|
Research Category:
Cell Signaling, Drug Discovery, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Mares A et al.
Miah AH,
View all...
Smith IED, Rackham M, Thawani AR, Cryan J, Haile PA, Votta BJ, Beal AM, Capriotti C, Reilly MA, Fisher DT, Zinn N, Bantscheff M, MacDonald TT, Vossenkamper A, Dace P, Churcher I, Benowitz AB, Watt G, Denyer J, Scott-Stevens P, Harling JD |
PMID: | 32198438 | |
Instrument Platform:
Simple Western |
Articles: |
(2020) Selective CDK6 degradation mediated by cereblon, VHL, and novel IAP-recruiting PROTACs Bioorg Med Chem Lett, 30 (9) :127106.
|
Research Category:
Cell Signaling, Drug Discovery, Gene Regulation, Immuno-Oncology, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Anderson NA et al.
Cryan J,
View all...
Ahmed A, Dai H, McGonagle GA, Rozier C, Benowitz AB |
PMID: | 32184044 | |
Instrument Platform:
Simple Western |
Articles: |
(2020) Androgen receptor degraders overcome common resistance mechanisms developed during prostate cancer treatment Neoplasia, 22 (2) :111-119.
|
Research Category:
Apoptosis, Cell Signaling, Gene Regulation, Immuno-Oncology, Metabolism, TPD and Induced Proximity |
Author: |
Kregel S et al.
Wang C,
View all...
Han X, Xiao L, Fernandez-Salas E, Bawa P, McCollum BL, Wilder-Romans K, Apel IJ, Cao X, Speers C, Wang S, Chinnaiyan AM |
PMID: | 31931431 | |
Instrument Platform:
Simple Western |
Articles: |
(2019) SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection Nat Commun, 10 (1) :5770.
|
Research Category:
Cell Signaling, Drug Discovery, Gene Regulation, Infectious Disease, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Gassen NC et al.
Niemeyer D,
View all...
Muth D, Corman VM, Martinelli S, Gassen A, Hafner K, Papies J, Mösbauer K, Zellner A, Zannas AS, Herrmann A, Holsboer F, Brack-Werner R, Boshart M, Müller-Myhsok B, Drosten C, Müller MA, Rein T |
PMID: | 31852899 | |
Instrument Platform:
Simple Western |
Articles: |
(2020) Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader Cell Chem Biol, 27 (1) :47-56.e15.
|
Research Category:
Immuno-Oncology, Metabolism, TPD and Induced Proximity |
Author: |
Potjewyd F et al.
Turner AW,
View all...
Beri J, Rectenwald JM, Norris-Drouin JL, Cholensky SH, Margolis DM, Pearce KH, Herring LE, James LI |
PMID: | 31831267 | |
Instrument Platform:
Simple Western |
Articles: |
(2019) BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design Nat Chem Biol, 15 (7) :672-680.
|
Research Category:
Immuno-Oncology, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Farnaby W et al.
Koegl M,
View all...
Roy MJ, Whitworth C, Diers E, Trainor N, Zollman D, Steurer S, Karolyi-Oezguer J, Riedmueller C, Gmaschitz T, Wachter J, Dank C, Galant M, Sharps B, Rumpel K, Traxler E, Gerstberger T, Schnitzer R, Petermann O, Greb P, Weinstabl H, Bader G, Zoephel A, Weiss-Puxbaum A, Ehrenhöfer-Wölfer K, Wöhrle S, Boehmelt G, Rinnenthal J, Arnhof H, Wiechens N, Wu MY, Owen-Hughes T, Ettmayer P, Pearson M, McConnell DB, Ciulli A |
PMID: | 31178587 | |
Instrument Platform:
Simple Western |
Articles: |
(2019) Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions J Med Chem, 62 (5) :2508-2520.
|
Research Category:
Cell Signaling, Immuno-Oncology, Metabolism, TPD and Induced Proximity |
Author: |
Popow J et al.
Arnhof H,
View all...
Bader G, Berger H, Ciulli A, Covini D, Dank C, Gmaschitz T, Greb P, Karolyi-Özguer J, Koegl M, McConnell DB, Pearson M, Rieger M, Rinnenthal J, Roessler V, Schrenk A, Spina M, Steurer S, Trainor N, Traxler E, Wieshofer C, Zoephel A, Ettmayer P |
PMID: | 30739444 | |
Instrument Platform:
Simple Western |
Articles: | |
Research Category:
Drug Discovery, Gene Regulation, Immuno-Oncology, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Zoppi V et al.
Hughes SJ,
View all...
Maniaci C, Testa A, Gmaschitz T, Wieshofer C, Koegl M, Riching KM, Daniels DL, Spallarossa A, Ciulli A |
PMID: | 30540463 | |
Instrument Platform:
Simple Western |
Articles: |
(2018) Delineating the role of cooperativity in the design of potent PROTACs for BTK Proc Natl Acad Sci U S A, 115 (31) :E7285-E7292.
|
Research Category:
Cell Signaling, Metabolism, Post-Translational Modifications, TPD and Induced Proximity |
Author: |
Zorba A et al.
Nguyen C,
View all...
Xu Y, Starr J, Borzilleri K, Smith J, Zhu H, Farley KA, Ding W, Schiemer J, Feng X, Chang JS, Uccello DP, Young JA, Garcia-Irrizary CN, Czabaniuk L, Schuff B, Oliver R, Montgomery J, Hayward MM, Coe J, Chen J, Niosi M, Luthra S, Shah JC, El-Kattan A, Qiu X, West GM, Noe MC, Shanmugasundaram V, Gilbert AM, Brown MF, Calabrese MF |
PMID: | 30012605 | |
Instrument Platform:
Simple Western |
Articles: |
(2018) A novel nano-immunoassay method for quantification of proteins from CD138-purified myeloma cells: biological and clinical utility Haematologica, 103 (5) :880-889.
|
Research Category:
Biomarkers, Immuno-Oncology, Metabolism, TPD and Induced Proximity |
Author: |
Misiewicz-Krzeminska I et al.
Corchete LA,
View all...
Rojas EA, Martínez-López J, García-Sanz R, Oriol A, Bladé J, Lahuerta JJ, Miguel JS, Mateos MV, Gutiérrez NC |
PMID: | 29545347 | |
Instrument Platform:
Simple Western |
Articles: |
(2018) ZB716, a steroidal selective estrogen receptor degrader (SERD), is orally efficacious in blocking tumor growth in mouse xenograft models Oncotarget, 9 (6) :6924-6937.
|
Research Category:
Gene Regulation, Immuno-Oncology, TPD and Induced Proximity |
Author: |
Guo S et al.
Zhang C,
View all...
Bratton M, Mottamal M, Liu J, Ma P, Zheng S, Zhong Q, Yang L, Wiese TE, Wu Y, Ellis MJ, Matossian M, Burow ME, Miele L, Houtman R, Wang G |
PMID: | 29467940 | |
Instrument Platform:
Simple Western |
Articles: |
(2016) Rational Design of a Boron-Modified Triphenylethylene (GLL398) as an Oral Selective Estrogen Receptor Downregulator ACS Med Chem Lett, 8 (1) :102-106.
|
Research Category:
Gene Regulation, Immuno-Oncology, TPD and Induced Proximity, Vaccines |
Author: |
Liu J et al.
Zheng S,
View all...
Guo S, Zhang C, Zhong Q, Zhang Q, Ma P, Skripnikova EV, Bratton MR, Wiese TE, Wang G |
PMID: | 28105283 | |
Instrument Platform:
Simple Western |
Articles: |
(2016) Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes PLoS One, 11 (9) :e0162384.
|
Research Category:
Bioprocess, Cell Signaling, Gene Regulation, Immuno-Oncology, Metabolism, TPD and Induced Proximity |
Author: |
Fan J et al.
Zareyan S,
View all...
Zhao W, Shimizu Y, Pfeifer TA, Tak JH, Isman MB, Van den Hoven B, Duggan ME, Wood MW, Wellington CL, Kulic I |
PMID: | 27598782 | |
Instrument Platform:
Simple Western |
Articles: |
(2016) N-Terminal-Based Targeted, Inducible Protein Degradation in Escherichia coli PLoS One, 11 (2) :e0149746.
|
Research Category:
Metabolism, TPD and Induced Proximity |
Author: |
Sekar K et al.
Gentile AM,
View all...
Bostick JW, Tyo KE |
PMID: | 26900850 |