ARHGAP20: Proteins and Enzymes

The ARHGAP20 gene encodes for a Rho GTPase-activating protein 20 that does so by converting them to an inactive GDP-bound state. It exists in four isoforms: 1ad is 1,191 amino acids long at 132 kDA, 1be is 1,165 amino acids long at 130 kDA, 1c is 1,168 amino acids long at 130 kDA, and 1e(1d) is 1,155 amino acids long at nearly 129 kDA. ARHGAP20 participates is signal transduction and Rho GTPase cycle and interacts with various genes such as RHOA, GRB2, SIRT5, TERF2, and BMPR1B. ARHGAP20 has been researched in lymphocytic leukemia.