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ASAH3: Lysates
Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. Has ahighly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but notD-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. May have a role in regulating the levels ofbioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids
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