CYP2F1: Proteins and Enzymes

CYP2F1, or Cytochrome P450 2F1, consists of a 491 amino acid isoform that is 56 kDa, and is involved in drug metabolism, cholesterol, steroid, and lipid synthesis, and the dealkylation of pentoxyresorufin, ethoxycoumarin, and propoxycoumarin. Current research is being conducted with CYP2F1 and a variety of diseases and disorders, including ovarian cancer, metastasis, cholesterol, vaccinia, and colorectal cancer, to determine the relationship between the protein and the disease. CYP2F1 interacts with ADH1A, ADH1B, ALDH1A3, EPHX1, and GSTA1 in biological processes such as metapathway biotransformation, biological oxidations, and CYP2E1 reactions.