EBOV GP Products
The GP glycoprotein encoded by the genome of Ebola family viruses is a critical molecule for the pathogenicity of Ebolavirus hemorrhagic viruses. It is processed into GP1 and GP2 fragments which remain disulfide linked. GP1 is entirely extracellular while GP2 is a transmembrane protein. GP expressed on virus infected cells can be shed by TACE mediated cleavage, liberating a disulfide linked complex of soluble GP1 and truncated GP2. GP binds to multiple C-type lectins on target cell surfaces, including CLEC10A/MGL, DC-SIGN, and DC-SIGNR. Following internalization, GP1 is cleaved by Cathepsin B and Cathepsin L and then interacts with Niemann-Pick C1 (NPC1) in the endosomal membrane.
Products:
46 results for "EBOV GP" in Products
46 results for "EBOV GP" in Products
EBOV GP Products
The GP glycoprotein encoded by the genome of Ebola family viruses is a critical molecule for the pathogenicity of Ebolavirus hemorrhagic viruses. It is processed into GP1 and GP2 fragments which remain disulfide linked. GP1 is entirely extracellular while GP2 is a transmembrane protein. GP expressed on virus infected cells can be shed by TACE mediated cleavage, liberating a disulfide linked complex of soluble GP1 and truncated GP2. GP binds to multiple C-type lectins on target cell surfaces, including CLEC10A/MGL, DC-SIGN, and DC-SIGNR. Following internalization, GP1 is cleaved by Cathepsin B and Cathepsin L and then interacts with Niemann-Pick C1 (NPC1) in the endosomal membrane.
Products:
Zaire ebolavirus Glycoprotein
Source: | CHO |
Accession #: | Q05320 |
Applications: | BA |
Recombinant Monoclonal Antibody.
Reactivity: | Viral |
Details: | Mouse IgG2a Monoclonal Clone #993408 |
Applications: | WB |
Source: | HEK293 |
Accession #: | NP_0066246.1 |
Applications: | BA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #02 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG2B Monoclonal Clone #A1-A6 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #06 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #02 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #06 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #06 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #02 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #02 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #02 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #02 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #06 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #02 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #02 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #02 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #06 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #02 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #02 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #06 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #02 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #02 |
Applications: | ELISA |
Reactivity: | Ebola Virus |
Details: | Mouse IgG1 Monoclonal Clone #02 |
Applications: | ELISA |