GBP3: Proteins and Enzymes

The GBP3 gene codes for a member of the germinal center kinase family that demonstrates antiviral activity against influenza. One isoform is 595 amino acids long at 68 kDa and the other exists at 544 amino acids in length at nearly 62 kDA. The GBP3 gene has been studied in hypoglycemic comas, hepatitis B, and influenza and interacts in pathways of interferon gamma signaling, cytokine signaling in the immune system, and expression of IFNG-stimulated genes. It interacts with genes MAP4K4, NFATC2, and FAM107B.