GCOM1: Lysates

GCOM1 is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts. The GRINL1A gene uses a downstream promoter for transcription and also has multiple alternatively spliced variants. [provided by RefSeq]. Transcript Variant: This variant (13), also called Gup2, has multiple differences in the coding region, compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 8) has a distinct C-terminus and is shorter than isoform 1.