Heterogeneous Nuclear Ribonucleoprotein (A1-like) Products

The HNRNPA1 gene encodes a heterogeneous nuclear ribonucleoprotein A1-like (part of the hnRNPs) that functions in various processes such as the ordering of pre-mRNA into hnRNP particles, the transport of poly(A) mRNA to the cytoplams from the nucleus, as well as plays a part in the regulation of splice site selection. Additionally, HNRNPA1 also functions in HCV RNA replication. This gene functions in mRNA splicing and processing, coregulation of adrogen receptor activity, and in translational control. it has been known to interact with various genes such as DDV5, ILF3, DDX17, HNRNPC, and ABHD16A. HNRNPA1 has been researched in various diseases including: cystic fibrosis, colorectal cancer, crohn's disease, spinal cord disease, human t-cell leukemia virus type 1 and type 2, muscular atrophy, stomatitis, and metastasis efficiency.