JAB1 Products
JAB1 (Jun activation domain binding protein-1), also called COPS5 or CSN5 (COP9 signalosome-5), is a 334 amino acid, 38 kDa protein that is a subunit of the COP9 signalosome complex. It mediates cytosolic translocation of the cell cycle inhibitory protein, CDKN1B/p27Kip1, for degradation, thus promoting proliferation. It is widely expressed, especially in proliferating cells, and upregulates granulopoiesis when overexpressed.
42 results for "JAB1" in Products
42 results for "JAB1" in Products
JAB1 Products
JAB1 (Jun activation domain binding protein-1), also called COPS5 or CSN5 (COP9 signalosome-5), is a 334 amino acid, 38 kDa protein that is a subunit of the COP9 signalosome complex. It mediates cytosolic translocation of the cell cycle inhibitory protein, CDKN1B/p27Kip1, for degradation, thus promoting proliferation. It is widely expressed, especially in proliferating cells, and upregulates granulopoiesis when overexpressed.
| Reactivity: | Human, Mouse, Rat, Drosophila |
| Details: | Mouse IgG2B Monoclonal Clone #2A10.8 |
| Applications: | IHC, WB, ICC/IF, IP |
![Western Blot: JAB1 Antibody (2A10.8) [NB120-495]](https://resources.bio-techne.com/images/products/JAB1-Antibody-2A10-Western-Blot-NB120-495-img0006.jpg "Western Blot: JAB1 Antibody (2A10.8) [NB120-495]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #3X5F0 |
| Applications: | IHC, WB, ELISA, ICC/IF, ChIP |
![Western Blot: JAB1 Antibody (3X5F0) [NBP3-16328]](https://resources.bio-techne.com/images/products/JAB1-Antibody-3X5F0-Western-Blot-NBP3-16328-img0006.jpg "Western Blot: JAB1 Antibody (3X5F0) [NBP3-16328]")
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #687409 |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2B12 |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: JAB1 Antibody (OTI2B12) [NBP2-01813]](https://resources.bio-techne.com/images/products/JAB1-Antibody-2B12-Western-Blot-NBP2-01813-img0026.jpg "Western Blot: JAB1 Antibody (OTI2B12) [NBP2-01813]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse, Drosophila |
| Details: | Mouse IgG2A Monoclonal Clone #8H8.5 |
| Applications: | WB, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: JAB1 Antibody [NBP1-84370]](https://resources.bio-techne.com/images/products/JAB1-Antibody-Western-Blot-NBP1-84370-img0006.jpg "Western Blot: JAB1 Antibody [NBP1-84370]")
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: JAB1 Antibody [NBP2-55578]](https://resources.bio-techne.com/images/products/JAB1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-55578-img0001.jpg "Immunocytochemistry/ Immunofluorescence: JAB1 Antibody [NBP2-55578]")
| Applications: | WB |
![Western Blot: JAB1 Overexpression Lysate [NBL1-09383]](https://resources.bio-techne.com/images/products/JAB1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-09383-img0002.jpg "Western Blot: JAB1 Overexpression Lysate [NBL1-09383]")
| Applications: | AC |
| Applications: | AC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2B12 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2B12 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2B12 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2B12 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2B12 |
| Applications: | IHC, WB, ICC/IF |
Potent and selective CSN5 (COP9 signalosome) inhibitor
| Chemical Name: | 3-(Difluoromethyl)-N-(6-((5S,6S)-6-hydroxy-6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepin-5-yl)-[1,10-biphenyl]-3-yl)-1-isopropyl-1H-pyrazole-5-carboxamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2B12 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2B12 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2B12 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2B12 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2B12 |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2B12 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #OTI2B12 |
| Applications: | IHC, WB, ICC/IF |