Lyn Products
The nonreceptor tyrosine kinase Lyn (lck/yes-related novel tyrosine kinase) is widely expressed, and the predominant Src family member present in B cells. Activation of Lyn occurs upon its association with cell surface receptors such as BCR and CD40. Analyses from both loss- and gain-of-function mutant mice have revealed that Lyn is an essential regulator of B cell activation, maturation, and tolerance.
46 results for "Lyn" in Products
46 results for "Lyn" in Products
Lyn Products
The nonreceptor tyrosine kinase Lyn (lck/yes-related novel tyrosine kinase) is widely expressed, and the predominant Src family member present in B cells. Activation of Lyn occurs upon its association with cell surface receptors such as BCR and CD40. Analyses from both loss- and gain-of-function mutant mice have revealed that Lyn is an essential regulator of B cell activation, maturation, and tolerance.
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #LYN-01 |
| Applications: | WB, ICC/IF, IP |
![Western Blot: Lyn Antibody (LYN-01)BSA Free [NB500-519]](https://resources.bio-techne.com/images/products/Lyn-Antibody-LYN-01-Western-Blot-NB500-519-img0001.jpg "Western Blot: Lyn Antibody (LYN-01)BSA Free [NB500-519]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #LYN-01 |
| Applications: | WB, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, ICC |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #338716 |
| Applications: | WB, Simple Western, ICC |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, IP |
![Western Blot: Lyn Antibody [NBP2-17188]](https://resources.bio-techne.com/images/products/Lyn-Antibody-Western-Blot-NBP2-17188-img0007.jpg "Western Blot: Lyn Antibody [NBP2-17188]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Lyn Antibody [NBP1-83072]](https://resources.bio-techne.com/images/products/Lyn-Antibody-Western-Blot-NBP1-83072-img0008.jpg "Western Blot: Lyn Antibody [NBP1-83072]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #SR2011 |
| Applications: | WB, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, IP |
![Western Blot: Lyn Antibody [NBP2-17189]](https://resources.bio-techne.com/images/products/Lyn-Antibody-Western-Blot-NBP2-17189-img0001.jpg "Western Blot: Lyn Antibody [NBP2-17189]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Lyn [p Tyr397] Antibody [NBP3-12926]](https://resources.bio-techne.com/images/products/Lyn-[p-Tyr397]-Antibody-Western-Blot-NBP3-12926-img0001.jpg "Western Blot: Lyn [p Tyr397] Antibody [NBP3-12926]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #5I5G8 |
| Applications: | WB |
| Applications: | PAGE |
![SDS-PAGE: Recombinant Human Lyn His Protein [NBP2-22945]](https://resources.bio-techne.com/images/products/Lyn-Protein-SDS-Page-NBP2-22945-img0001.jpg "SDS-PAGE: Recombinant Human Lyn His Protein [NBP2-22945]")
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: Lyn Antibody [NB100-93453]](https://resources.bio-techne.com/images/products/Lyn-Antibody-Western-Blot-NB100-93453-img0002.jpg "Western Blot: Lyn Antibody [NB100-93453]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JE44-75 |
| Applications: | WB, Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #HL122 |
| Applications: | WB |
| Applications: | ELISA |
| Applications: | ELISA |
| Applications: | WB |
| Applications: | AC |
Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins
Selective and highly potent Fgr and Lyn kinase inhibitor; orally bioavailable
| Chemical Name: | 3-[(6,7-Dimethoxy-4-quinazolinyl)oxy]-N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methylbenzamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Selective allosteric activator of Lyn kinase
| Chemical Name: | 5-(3-Methylphenoxy)-2(1H)-pyrimidinone |
| Purity: | ≥99% (HPLC) |
Potent and selective Src tyrosine kinase family inhibitor; anticancer; antiviral; orally bioavailable
| Alternate Names: | AZD 0530 |
| Chemical Name: | N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #LYN-01 |
| Applications: | WB, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #LYN-01 |
| Applications: | WB, ICC/IF, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #LYN-01 |
| Applications: | WB, ICC/IF, IP |