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MTGR1 Products

In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.
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43 results for "MTGR1" in Products

43 results for "MTGR1" in Products

MTGR1 Products

In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.
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Applications: IHC, WB
Reactivity: Human
Applications: IHC, WB, ELISA
Reactivity: Human
Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Catalog #: H00009139-Q01
Applications: WB, ELISA, MA, AP
Applications: WB, ELISA, MA, AP, PAGE
Applications: WB, ELISA
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB
Applications: WB, ELISA
Reactivity: Human
Applications: WB
Reactivity: Mouse
Applications: ICC/IF
Reactivity: Human
Applications: AC
Applications: AC
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
Applications: WB, IP
Reactivity: Human
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