MTGR1 Products
In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.
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43 results for "MTGR1" in Products
43 results for "MTGR1" in Products
MTGR1 Products
In acute myeloid leukemia, especially in the M2 subtype, the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 (AML1) gene fused to the 3'-region of the CBFA2T1 (MTG8) gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene binds to the AML1-MTG8 complex and may be important in promoting leukemogenesis. Several transcript variants are thought to exist for this gene, but the full-length natures of only three have been described.
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Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB |
Applications: IHC, WB, ELISA
Reactivity:
Human
Reactivity: | Human |
Details: | Mouse IgG2b Kappa Monoclonal Clone #2C10 |
Applications: | IHC, WB, ELISA |
Applications: WB, ELISA, ICC/IF
Reactivity:
Human,
Mouse,
Rat
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, ICC/IF |
Applications: | WB, ELISA, MA, AP |
Applications: | WB, ELISA, MA, AP, PAGE |
Reactivity: | Human |
Details: | Mouse IgG2a Kappa Monoclonal Clone #3A2 |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Mouse IgG2b Kappa Monoclonal Clone #3G8 |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, IP |
Applications: | WB |
Reactivity: | Human |
Details: | Mouse IgG2b Kappa Monoclonal Clone #2H8 |
Applications: | WB, ELISA |
Reactivity: | Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | ICC/IF |
Applications: | AC |
Applications: | AC |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, IP |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, IP |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, IP |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, IP |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, IP |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, IP |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, IP |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, IP |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, IP |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, IP |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, IP |