NAPA Products
The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37%, 60%, and 67% identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively. Platelets contain some of the same proteins, including NSF, p115/TAP, alpha-SNAP, gamma-SNAP, and the t-SNAREs syntaxin-2 and syntaxin-4, that are used in many vesicular transport processes in other cell types. Platelet exocytosis uses a molecular mechanism similar to that used by other secretory cells, such as neurons, although the proteins used by the platelet and their modes of regulation may be quite different. [provided by RefSeq]
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42 results for "NAPA" in Products
42 results for "NAPA" in Products
NAPA Products
The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37%, 60%, and 67% identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively. Platelets contain some of the same proteins, including NSF, p115/TAP, alpha-SNAP, gamma-SNAP, and the t-SNAREs syntaxin-2 and syntaxin-4, that are used in many vesicular transport processes in other cell types. Platelet exocytosis uses a molecular mechanism similar to that used by other secretory cells, such as neurons, although the proteins used by the platelet and their modes of regulation may be quite different. [provided by RefSeq]
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Applications: IHC, WB, ICC/IF, IP
Reactivity:
Human,
Mouse,
Rat
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, IP |
Applications: IHC, WB, ICC/IF
Reactivity:
Human,
Mouse,
Rat
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #SR1544 |
Applications: | IHC, WB, ICC/IF |
Applications: IHC, WB
Reactivity:
Human,
Mouse,
Rat
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB |
Applications: WB, ELISA, ICC/IF, IP
Reactivity:
Human
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, ICC/IF, IP |
Applications: WB, ELISA
Reactivity:
Human,
Mouse,
Rat,
Primate,
Porcine
Reactivity: | Human, Mouse, Rat, Primate, Porcine |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #7Z6F6 |
Applications: | WB |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
Applications: | ELISA |
Applications: | WB |
Applications: | PAGE |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | ELISA |
Applications: | AC |
Applications: | AC |
Applications: WB, ELISA, ICC/IF, IP
Reactivity:
Human
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, ICC/IF, IP |
Applications: WB, ELISA, ICC/IF, IP
Reactivity:
Human
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, ICC/IF, IP |
Applications: WB, ELISA, ICC/IF, IP
Reactivity:
Human
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, ICC/IF, IP |
Applications: WB, ELISA, ICC/IF, IP
Reactivity:
Human
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, ICC/IF, IP |
Applications: WB, ELISA, ICC/IF, IP
Reactivity:
Human
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, ICC/IF, IP |
Applications: WB, ELISA, ICC/IF, IP
Reactivity:
Human
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, ICC/IF, IP |
Applications: WB, ELISA, ICC/IF, IP
Reactivity:
Human
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, ICC/IF, IP |
Applications: WB, ELISA, ICC/IF, IP
Reactivity:
Human
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, ICC/IF, IP |
Applications: WB, ELISA, ICC/IF, IP
Reactivity:
Human
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, ICC/IF, IP |
Applications: WB, ELISA, ICC/IF, IP
Reactivity:
Human
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, ICC/IF, IP |
Applications: WB, ELISA, ICC/IF, IP
Reactivity:
Human
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ELISA, ICC/IF, IP |