V1b Vasopressin R/AVPR1B Products
AVPR1B acts as a receptor for arginine vasopressin. AVPR1B belongs to the subfamily of G protein-coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. AVPR1B is primarily located in the anterior pituitary, where it stimulates ACTH release. AVPR1B is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome.
11 results for "V1b Vasopressin R/AVPR1B" in Products
11 results for "V1b Vasopressin R/AVPR1B" in Products
V1b Vasopressin R/AVPR1B Products
AVPR1B acts as a receptor for arginine vasopressin. AVPR1B belongs to the subfamily of G protein-coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. AVPR1B is primarily located in the anterior pituitary, where it stimulates ACTH release. AVPR1B is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome.
Applications: | WB |
Reactivity: | Human, Rat, Canine, Bovine, Porcine, +3 More |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB (-), ICC/IF (-) |
Reactivity: | Human, Monkey |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
Applications: | AC |
Synthetic vasopressin analog; V1B and V2 agonist
Purity: | ≥95% (HPLC) |
Potent and selective vasopressin V1B antagonist
Alternate Names: | Nelivaptan |
Chemical Name: | (2S,4R)-1-[(3R)-5-Chloro-1-[(2,4-dimethoxyphenyl)sulfonyl]-2,3-dihydro-3-(2-methoxyphenyl)-2-oxo-1H-indol-3-yl]-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide |
Purity: | ≥98% (HPLC) |
Orally active vasopressin V1 antagonist
Chemical Name: | N-[3-[4-[[4-(3,4-Dihydro-2-oxo-1(2H)quinolinyl)-1-piperidinyl]carbonyl]phenoxy]propyl]-acetamide |
Purity: | ≥98% (HPLC) |
Potent and selective V1B receptor antagonist; orally bioavailable
Chemical Name: | 2-(3-Chloro-4-fluorophenyl)-N-(1-methylethyl)-6-[3-(4-morpholinyl)propoxy]-4-oxo-pyrido[2,3-d]pyrimidine-3(4H)-acetamide hydrochloride |
Purity: | ≥98% (HPLC) |