CCL2/JE/MCP-1 Products
CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.
171 results for "CCL2/JE/MCP-1" in Products
171 results for "CCL2/JE/MCP-1" in Products
CCL2/JE/MCP-1 Products
CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.
| Sensitivity: | 0.666 pg/mL |
| Applications: | ELISA |
| Assay Range: | 7.81 - 500 pg/mL (Cell Culture Supernates, Tissue Lysates, Tissue Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Sensitivity: | 10 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine) |
| Assay Range: | 3.91 - 250 pg/mL |
| Applications: | ELISA |
| Source: | E. coli |
| Accession #: | Q5SVU3 |
| Applications: | BA |
| Assay Range: | 15.6 - 1,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #23007 |
| Applications: | WB, IHC, Dual ISH-IHC, Neut |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #24822 |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #123616 |
| Applications: | Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #23002 |
| Applications: | IHC |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Source: | E. coli |
| Accession #: | P13500.1 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Source: | NS0 |
| Accession #: | P14844 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #123616 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Canine |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC, Neut |
| Reactivity: | Canine |
| Details: | Mouse IgG1 Monoclonal Clone #280702 |
| Applications: | WB, ICC, Neut |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #23007R |
| Applications: | WB, Neut |
| Reactivity: | Canine |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC |
Recombinant Monoclonal Antibody.
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #123616R |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #24822 |
| Applications: | ICFlow |
| Reactivity: | Canine |
| Details: | Mouse IgG2b Monoclonal Clone #280707 |
| Applications: | WB |