CCL2/JE/MCP-1 Products
CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.
111 results for "CCL2/JE/MCP-1" in Products
111 results for "CCL2/JE/MCP-1" in Products
CCL2/JE/MCP-1 Products
CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.
| Sensitivity: | 0.666 pg/mL |
| Applications: | ELISA |
| Assay Range: | 7.81 - 500 pg/mL (Cell Culture Supernates, Tissue Lysates, Tissue Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Assay Range: | 3.91 - 250 pg/mL |
| Applications: | ELISA |
| Source: | E. coli |
| Accession #: | Q5SVU3 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #123616 |
| Applications: | Neut |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #123616 |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #123616R |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #123616R |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #123616R |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #123616R |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #123616R |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #123616R |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #123616R |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #123616R |
| Applications: | Flow |
Recombinant Monoclonal Antibody.
| Reactivity: | Mouse |
| Details: | Rat IgG2B Monoclonal Clone #123616R |
| Applications: | Flow |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #001 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #017 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #001 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #017 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #001 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #001 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #017 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Mouse |
| Details: | Rabbit IgG Monoclonal Clone #017 |
| Applications: | ELISA |