Cell Cycle Inhibitors Products
Cell cycle inhibitors slow or stop cell cycle progression via different mechanisms. Cell cycle arrest can be induced at different stages. This can decrease the rate of cell division and the number of cells that are actively cycling.
20 results for "Cell Cycle Inhibitors" in Products
20 results for "Cell Cycle Inhibitors" in Products
Cell Cycle Inhibitors Products
Cell cycle inhibitors slow or stop cell cycle progression via different mechanisms. Cell cycle arrest can be induced at different stages. This can decrease the rate of cell division and the number of cells that are actively cycling.
mRNA splicing inhibitor; antitumor
| Chemical Name: | (4R,7R,8S,9E,11S,12S)-8-(Acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyloxacyclododec-9-en-2-one |
| Purity: | ≥95% |
Potent and selective CDK7 inhibitor; induces cell cycle arrest
| Chemical Name: | N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[[4-[(1-oxo-2-propen-1-yl)amino]benzoyl]amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide |
| Purity: | ≥95% |
BET bromodomain inhibitor; arrests cell cycle at G1 phase
| Chemical Name: | (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
| Purity: | ≥98% |
Stimulates RhoA activation; antiproliferative agent that slows cell cycle progression
| Chemical Name: | (2S,3R,4S,4aR)-3,4,4a,5-Tetrahydro-2,3,4,7-tetrahydroxy-(1,3)dioxolo(4,5-j)phenanthridin-6(2H)-one |
| Purity: | ≥98% |
Stabilizes G-quadruplexes; induces DNA damage and cell cycle arrest
| Chemical Name: | 4-(2-Aminoethoxy)N2,N6-bis[(4-(2-aminoethoxy)-2-quinolinyl]-2,6-pyridinecarboxamide pentahydrochloride |
| Purity: | ≥95% (HPLC) |
Cytotoxic agent
| Chemical Name: | N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid |
| Purity: | ≥99% (HPLC) |
Soluble guanylyl cyclase (sGC) activator; induces G1 cell cycle arrest
| Chemical Name: | 3-(5'-Hydroxymethyl-2'-furyl)-1-benzyl indazole |
| Purity: | ≥99% |
Cdk inhibitor
| Chemical Name: | (2R)-2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol |
| Purity: | ≥98% |
Potent and selective PIP4K2A inhibitor
| Chemical Name: | (R)-2-((3-Cyano-2-(2'-fluoro-3'-methyl-[1,1'-biphenyl]-4-yl)-1,7-naphthyridin-4-yl)amino)butanoic acid |
| Purity: | ≥98% |
Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9
| Chemical Name: | 4-[2-Methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-2-pyrimidinamine |
| Purity: | ≥99% (HPLC) |
Potent and selective Cdc7 inhibitor
| Alternate Names: | BMS 863233 |
| Chemical Name: | 8-Chloro-2-(2S)-2-pyrrolidinylbenzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride |
| Purity: | ≥99% (HPLC) |
High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor
| Chemical Name: | 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide |
| Purity: | ≥98% (HPLC) |
Potent and selective MST3 kinase binding inhibitor
| Chemical Name: | 8-(4-Aminobutyl)-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(1,3-dihydroxypropan-2-ylamino)pyrido[2,3-d]pyrimidin-7-one trihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective mTOR inhibitor
| Chemical Name: | N-[4-[4-(4-Morpholinyl)-1-[1-(3-pyridinylmethyl)-4-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-carbamic acid methyl ester dihydrochloride |
| Purity: | ≥98% |
Potent covalent CDK14 and CDK16 inhibitor; also inhibits other TAIRE kinase family members
| Chemical Name: | N-[1-[[3-[[(2E)-4-(Dimethylamino)-1-oxo-2-buten-1-yl]amino]phenyl]sulfonyl]-4-piperidinyl]-4-[(2,4,6- trichlorobenzoyl)amino]-1H-pyrazole-3-carboxamide |
| Purity: | ≥98% |
Potent CDK14 and CDK16 inhibitor; displays reversible inhibition of CDK14
| Chemical Name: | N-(1-((3-(4-(Dimethylamino)butanamido)phenyl)sulfonyl)piperidin-4-yl)-4-(2,4,6-trichlorobenzamido)-1H-pyrazole-3-carboxamide |
| Purity: | ≥98% |
Potent cdk inhibitor
| Chemical Name: | 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol |
| Purity: | ≥98% (HPLC) |
Suppresses ROS-induced activation of the NLRP3 inflammasome; antimalarial
| Chemical Name: | 4-Oxo-4-(((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-3H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)oxy)butanoic acid |
| Purity: | ≥98% (HPLC) |
Cytotoxic nucleoside analog; inhibits RNA synthesis
| Chemical Name: | 6-Amino-8-chloropurine riboside |
| Purity: | ≥98% |
Inhibits c-Myc-Max dimerization
| Chemical Name: | 5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone |
| Purity: | ≥99% |
