Chitinase 3-like 1/YKL-40 Products
Chitinase 3-like 1/YKL-40 (CHI3L1), also called BRP39 in mouse, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family although it does not show chitotriosidase activity. CHI3L1 is expressed by articular chondrocytes, synovial cells, activated monocyte-derived macrophages, neutrophils, endothelial cells, vascular smooth muscle cells, and some cancer cells.
CHI3L1 binds to chitin and heparins, and it enhances cell adhesion, proliferation and tumor angiogenesis. Circulating CHI3L1 is elevated during inflammation and connective tissue remodeling such as arthritis, chronic obstructive pulmonary disease, diabetes, cardiovascular disease, inflammatory bowel disease, and liver cirrhosis. It is frequently upregulated in glioblastoma, myxoid chondrosarcoma, melanoma, and carcinomas of the breast, thyroid, colon, lung, kidney, and ovary.
Products:
95 results for "Chitinase 3-like 1/YKL-40" in Products
95 results for "Chitinase 3-like 1/YKL-40" in Products
Chitinase 3-like 1/YKL-40 Products
Chitinase 3-like 1/YKL-40 (CHI3L1), also called BRP39 in mouse, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family although it does not show chitotriosidase activity. CHI3L1 is expressed by articular chondrocytes, synovial cells, activated monocyte-derived macrophages, neutrophils, endothelial cells, vascular smooth muscle cells, and some cancer cells.
CHI3L1 binds to chitin and heparins, and it enhances cell adhesion, proliferation and tumor angiogenesis. Circulating CHI3L1 is elevated during inflammation and connective tissue remodeling such as arthritis, chronic obstructive pulmonary disease, diabetes, cardiovascular disease, inflammatory bowel disease, and liver cirrhosis. It is frequently upregulated in glioblastoma, myxoid chondrosarcoma, melanoma, and carcinomas of the breast, thyroid, colon, lung, kidney, and ovary.
Products:
| Sensitivity: | 8.15 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
Simple Plex Human Chitinase 3-like 1 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, ICC |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Simple Western, IP |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Sensitivity: | 16 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #321924 |
| Applications: | WB |
Control for use with Human Chitinase 3-like 1 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
| Source: | NS0 |
| Accession #: | P36222 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | Q61362 |
| Applications: | BA |
Simple Plex Mouse/Rat Chitinase 3-like 1 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD10, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #101 |
| Applications: | ELISA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #Brown U. patent anti-CHI3L1 |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human, Primate |
| Details: | Rat IgG1 Monoclonal Clone #384327 |
| Reactivity: | Human, Primate |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
Control for use with Mouse/Rat Chitinase 3-Like 1 Simple Plex Assay Cartridge Kit
| Applications: | Simple Plex |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #CL12241 |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: Chitinase 3-like 1 Antibody [NBP3-21212] -](https://resources.bio-techne.com/images/products/nbp3-21212_mouse-chitinase-3-like-1-mab-cl12241-45202315534325.jpg "Immunohistochemistry-Paraffin: Chitinase 3-like 1 Antibody [NBP3-21212] -")
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #CL12314 |
| Applications: | IHC, WB |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human, Monkey, Virus |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Chitinase 3-like 1/YKL-40 Antibody [NBP1-57913]](https://resources.bio-techne.com/images/products/Chitinase-3-like-1-Antibody-Western-Blot-NBP1-57913-img0001.jpg "Western Blot: Chitinase 3-like 1/YKL-40 Antibody [NBP1-57913]")
Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies
