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Chitinase 3-like 1/YKL-40 Products

Chitinase 3-like 1/YKL-40 (CHI3L1), also called BRP39 in mouse, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family although it does not show chitotriosidase activity. CHI3L1 is expressed by articular chondrocytes, synovial cells, activated monocyte-derived macrophages, neutrophils, endothelial cells, vascular smooth muscle cells, and some cancer cells.

CHI3L1 binds to chitin and heparins, and it enhances cell adhesion, proliferation and tumor angiogenesis. Circulating CHI3L1 is elevated during inflammation and connective tissue remodeling such as arthritis, chronic obstructive pulmonary disease, diabetes, cardiovascular disease, inflammatory bowel disease, and liver cirrhosis. It is frequently upregulated in glioblastoma, myxoid chondrosarcoma, melanoma, and carcinomas of the breast, thyroid, colon, lung, kidney, and ovary.

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101 results for "Chitinase 3-like 1/YKL-40" in Products

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101 results for "Chitinase 3-like 1/YKL-40" in Products

Chitinase 3-like 1/YKL-40 Products

Chitinase 3-like 1/YKL-40 (CHI3L1), also called BRP39 in mouse, is a 39 kDa glycoprotein member of the glycosyl hydrolase 18 family although it does not show chitotriosidase activity. CHI3L1 is expressed by articular chondrocytes, synovial cells, activated monocyte-derived macrophages, neutrophils, endothelial cells, vascular smooth muscle cells, and some cancer cells.

CHI3L1 binds to chitin and heparins, and it enhances cell adhesion, proliferation and tumor angiogenesis. Circulating CHI3L1 is elevated during inflammation and connective tissue remodeling such as arthritis, chronic obstructive pulmonary disease, diabetes, cardiovascular disease, inflammatory bowel disease, and liver cirrhosis. It is frequently upregulated in glioblastoma, myxoid chondrosarcoma, melanoma, and carcinomas of the breast, thyroid, colon, lung, kidney, and ovary.

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Simple Plex Human Chitinase 3-like 1 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: WB, Simple Western, IHC, ICC
Reactivity: Human
Applications: WB
Reactivity: Mouse
Applications: Ctrl, Simple Plex

Control for use with Human Chitinase 3-like 1 Simple Plex Cartridge Kit

Applications: Simple Plex

Simple Plex Mouse/Rat Chitinase 3-like 1 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD10, and wash buffer.

Applications: WB, Simple Western, IP
Reactivity: Mouse
Applications: ELISA
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Reactivity: Human, Primate
Applications: WB
Reactivity: Human, Primate
Applications: Simple Plex

Control for use with Mouse/Rat Chitinase 3-Like 1 Simple Plex Assay Cartridge Kit

Applications: IHC, WB
Reactivity: Human
Applications: IHC, WB
Reactivity: Human
Applications: WB
Reactivity: Mouse

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

Applications: IHC, WB, ICC/IF
Reactivity: Human, Monkey, Virus
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