GPR55 Products
Members of the G protein-coupled receptor (GPCR) family, such as GPR55, play important roles in signal transduction from the external environment to the inside of the cell. GPR55 is a receptor for L-alpha-lysophosphatidylinositol (LPI). LPI induces Ca2+ release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. GPR55 is expressed in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain or in the liver. It is expressed in osteoclasts and osteoblasts. GPR55 may play a role in bone physiology by regulating osteoclast number and function. GPR55 may also be involved in hyperalgesia associated with inflammatory and neuropathic pain.
18 results for "GPR55" in Products
18 results for "GPR55" in Products
GPR55 Products
Members of the G protein-coupled receptor (GPCR) family, such as GPR55, play important roles in signal transduction from the external environment to the inside of the cell. GPR55 is a receptor for L-alpha-lysophosphatidylinositol (LPI). LPI induces Ca2+ release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. GPR55 is expressed in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain or in the liver. It is expressed in osteoclasts and osteoblasts. GPR55 may play a role in bone physiology by regulating osteoclast number and function. GPR55 may also be involved in hyperalgesia associated with inflammatory and neuropathic pain.
Reactivity: | Human, Canine, Equine |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
Reactivity: | Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Reactivity: | Mouse, Rat |
Details: | Rabbit Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB |
Applications: | WB |
Potent CB1 antagonist; also GPR55 agonist
Chemical Name: | N-(Piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide |
Purity: | ≥99% (HPLC) |
Selective GPR55 agonist. FAAH and PAA substrate
Alternate Names: | PEA |
Chemical Name: | N-(2-Hydroxyethyl)hexadecanamide |
Natural cannabinoid; GPR55 antagonist, weak CB1 antagonist, CB2 inverse agonist and AMT inhibitor
Alternate Names: | CBD |
Chemical Name: | 2-[(1R,6R)-3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol |
Purity: | ≥99% (HPLC) |
Endogenous and non-selective CB agonist; potent GPR55 agonist
Alternate Names: | 2-AG,Arachidonoylglycerol |
Chemical Name: | (5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester |
Potent GPR55 agonist
Chemical Name: | 5-Methyl-4-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-1,3-benzenediol |
Purity: | ≥97% (HPLC) |
Lipid mediator, anorexic actions; also GPR55 and PPARα agonist
Chemical Name: | (9Z)-N-(2-Hydroxyethyl)-9-octadecenamide |
Purity: | ≥99% (HPLC) |
Selective GPR55 antagonist
Chemical Name: | 4-[4,6-Dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoic acid |
Purity: | ≥98% (HPLC) |
Potent, selective GPR55 antagonist
Alternate Names: | CID 1261822 |
Chemical Name: | N-[4-[[(3,4-Dimethyl-5-isoxazolyl)amino]sulfonyl]phenyl]-6,8-dimethyl-2-(2-pyridinyl)-4-quinolinecarboxamide |
Purity: | ≥98% (HPLC) |
Endogenous and non-selective CB agonist
Alternate Names: | Arachidonylethanolamide,AEA |
Chemical Name: | N-(2-Hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide |
Purity: | ≥98% (HPLC) |
Selective GPR55 agonist; also promotes NSC proliferation and differentiation
Alternate Names: | CID 20440433 |
Chemical Name: | 3-[[4-(2,3-Dimethylphenyl)-1-piperazinyl]carbonyl]-N,N-dimethyl-4-(1-pyrrolidinyl)benzenesulfonamide |
Purity: | ≥98% (HPLC) |