mGluR5 Products
Human metabotropic glutamate receptor 5 (mGluR5; also mGluR5b) is a 150 kDa, 7-transmembrane glycoprotein that belongs to group I of the C-family of G-protein coupled receptors. mGluR5 is constitutively expressed and regulates neuronal ion channel activity. Human mGluR5 is 1212 amino acids (aa) in length and contains an extracellular domain (ECD) of 558 amino acids. Through its ECD, mGluR5 either homodimerizes or heterodimerizes with the Ca2+-sensor receptor. There is one alternate splice form (mGluR5a) that shows a 32 aa deletion between aa 877 - 908 in the cytoplasmic tail. Over aa 19 - 509, human mGluR5 is 98% aa identical to mouse, rat, and canine mGluR5.
58 results for "mGluR5" in Products
58 results for "mGluR5" in Products
mGluR5 Products
Human metabotropic glutamate receptor 5 (mGluR5; also mGluR5b) is a 150 kDa, 7-transmembrane glycoprotein that belongs to group I of the C-family of G-protein coupled receptors. mGluR5 is constitutively expressed and regulates neuronal ion channel activity. Human mGluR5 is 1212 amino acids (aa) in length and contains an extracellular domain (ECD) of 558 amino acids. Through its ECD, mGluR5 either homodimerizes or heterodimerizes with the Ca2+-sensor receptor. There is one alternate splice form (mGluR5a) that shows a 32 aa deletion between aa 877 - 908 in the cytoplasmic tail. Over aa 19 - 509, human mGluR5 is 98% aa identical to mouse, rat, and canine mGluR5.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #464818 |
| Applications: | WB, CyTOF-ready, ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #464823 |
| Applications: | IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IHC |
| Source: | NS0 |
| Accession #: | P41594 |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, IHC |
| Reactivity: | Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: mGluR5 Antibody [NBP3-13151]](https://resources.bio-techne.com/images/products/mGluR5-Antibody-Western-Blot-NBP3-13151-img0001.jpg "Western Blot: mGluR5 Antibody [NBP3-13151]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #464818 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #464818 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #464818 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #464818 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #464818 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #464818 |
| Applications: | ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #464818 |
| Applications: | ICFlow |
| Reactivity: | Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: mGluR5 Antibody [NBP3-13190]](https://resources.bio-techne.com/images/products/mGluR5-Antibody-Western-Blot-NBP3-13190-img0001.jpg "Western Blot: mGluR5 Antibody [NBP3-13190]")
| Reactivity: | Human, Mouse, Rat, Canine, Monkey, +8 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: mGluR5 Antibody - BSA Free [NBP1-02331]](https://resources.bio-techne.com/images/products/mGluR5-Antibody---BSA-Free-Immunohistochemistry-Paraffin-NBP1-02331-img0002.jpg "Immunohistochemistry-Paraffin: mGluR5 Antibody - BSA Free [NBP1-02331]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #464818 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #464818 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #464818 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #464818 |
| Applications: | WB, Flow, CyTOF-ready |
Selective mGlu5 agonist; sodium salt of CHPG (Cat. No. 1049)
| Chemical Name: | (RS)-2-Chloro-5-hydroxyphenylglycine sodium salt |
| Purity: | ≥99% (HPLC) |
Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors
| Chemical Name: | 2-Methyl-6-(phenylethynyl)pyridine hydrochloride |
| Purity: | ≥99% (HPLC) |
mGlu5 selective agonist
| Chemical Name: | (RS)-2-Chloro-5-hydroxyphenylglycine |
| Purity: | ≥99% (HPLC) |
Negative allosteric modulator of mGlu5 receptors
| Alternate Names: | Raseglurant |
| Chemical Name: | 2-[(3-Fluorophenyl)ethynyl]-4,6-dimethyl-3-pyridinamine hydrochloride |
| Purity: | ≥99% (HPLC) |
GluK1 antagonist; inhibits carbonic anhydrase (CA) II and IV; also positive allosteric modulator of GABAA receptors
| Alternate Names: | Topamax |
| Chemical Name: | 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamate |
| Purity: | ≥99% (HPLC) |
