Thrombopoietin/Tpo Products
Thrombopoietin (Tpo), is a key regulator of megakaryocytopoiesis and thrombopoiesis. It is principally produced in the liver and is bound and internalized by the receptor Tpo R/c-mpl. Defects in the Tpo-Tpo R signaling pathway are associated with a variety of platelet disorders. Tpo promotes the differentiation, proliferation, and maturation of megakaryocytes and their progenitors. Tpo additionally promotes platelet production, aggregation, ECM adhesion, and activation. Aside from its hematopoietic effects, Tpo is expressed in the brain where it promotes the apoptosis of hypoxia-sensitized neurons and inhibits neuronal differentiation by blocking NGF-induced signaling.
99 results for "Thrombopoietin/Tpo" in Products
99 results for "Thrombopoietin/Tpo" in Products
Thrombopoietin/Tpo Products
Thrombopoietin (Tpo), is a key regulator of megakaryocytopoiesis and thrombopoiesis. It is principally produced in the liver and is bound and internalized by the receptor Tpo R/c-mpl. Defects in the Tpo-Tpo R signaling pathway are associated with a variety of platelet disorders. Tpo promotes the differentiation, proliferation, and maturation of megakaryocytes and their progenitors. Tpo additionally promotes platelet production, aggregation, ECM adhesion, and activation. Aside from its hematopoietic effects, Tpo is expressed in the brain where it promotes the apoptosis of hypoxia-sensitized neurons and inhibits neuronal differentiation by blocking NGF-induced signaling.
| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #34817 |
| Applications: | Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #378120 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #34840 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #34863 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse Monoclonal Clone #1065103 |
| Applications: | WB |
| Source: | NS0 |
| Accession #: | P40225 |
| Applications: | BA |
Animal Free
| Source: | E. coli |
| Accession #: | NP_000451.1 |
| Applications: | BA |
| Sensitivity: | 18.5 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Source: | NS0 |
| Accession #: | P40226 |
| Applications: | BA |
| Sensitivity: | 20 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Citrate Plasma) |
| Source: | E. coli |
| Accession #: | NP_000451 |
| Applications: | BA |
| Source: | Sf 21 (baculovirus) |
| Accession #: | P40225 |
| Applications: | BA |
For use with catalog number DTP00B
| Applications: | ELISA, Ctrl |
Analyzed by SEC-MALS. His-tag (HEK-293-expressed)
| Source: | HEK293 |
| Accession #: | P40225.1 |
| Applications: | BA |
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: Thrombopoietin/THPO Antibody [NBP1-59293]](https://resources.bio-techne.com/images/products/Thrombopoietin-Antibody-Western-Blot-NBP1-59293-img0002.jpg "Western Blot: Thrombopoietin/THPO Antibody [NBP1-59293]")
| Assay Range: | 93.8 - 6,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #1B11 |
| Applications: | WB, ELISA, Flow, CyTOF-ready |
![Western Blot: Thrombopoietin/THPO Antibody (1B11)BSA Free [NBP2-37498]](https://resources.bio-techne.com/images/products/Thrombopoietin-Tpo-Antibody-1B11-Western-Blot-NBP2-37498-img0002.jpg "Western Blot: Thrombopoietin/THPO Antibody (1B11)BSA Free [NBP2-37498]")
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Source: | NS0 |
| Accession #: | P49745 |
| Applications: | BA |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #2 |
| Applications: | ELISA |
