Thrombopoietin/Tpo Products
Thrombopoietin (Tpo), is a key regulator of megakaryocytopoiesis and thrombopoiesis. It is principally produced in the liver and is bound and internalized by the receptor Tpo R/c-mpl. Defects in the Tpo-Tpo R signaling pathway are associated with a variety of platelet disorders. Tpo promotes the differentiation, proliferation, and maturation of megakaryocytes and their progenitors. Tpo additionally promotes platelet production, aggregation, ECM adhesion, and activation. Aside from its hematopoietic effects, Tpo is expressed in the brain where it promotes the apoptosis of hypoxia-sensitized neurons and inhibits neuronal differentiation by blocking NGF-induced signaling.
94 results for "Thrombopoietin/Tpo" in Products
94 results for "Thrombopoietin/Tpo" in Products
Thrombopoietin/Tpo Products
Thrombopoietin (Tpo), is a key regulator of megakaryocytopoiesis and thrombopoiesis. It is principally produced in the liver and is bound and internalized by the receptor Tpo R/c-mpl. Defects in the Tpo-Tpo R signaling pathway are associated with a variety of platelet disorders. Tpo promotes the differentiation, proliferation, and maturation of megakaryocytes and their progenitors. Tpo additionally promotes platelet production, aggregation, ECM adhesion, and activation. Aside from its hematopoietic effects, Tpo is expressed in the brain where it promotes the apoptosis of hypoxia-sensitized neurons and inhibits neuronal differentiation by blocking NGF-induced signaling.
| Source: | E. coli |
| Accession #: | NP_000451.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | NP_000451.1 |
| Applications: | BA |
| Source: | E. coli |
| Accession #: | NP_000451.1 |
| Applications: | BA |
| Reactivity: | Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #378120 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #34840 |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #34863 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1065103 |
| Applications: | WB |
| Details: | Mouse IgG1 Monoclonal Clone #1053909 |
| Applications: | IHC |
| Sensitivity: | 18.5 pg/mL |
| Applications: | ELISA |
| Assay Range: | 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Source: | NS0 |
| Accession #: | P40225 |
| Applications: | BA |
Animal Free
| Source: | E. coli |
| Accession #: | NP_000451.1 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | P40226 |
| Applications: | BA |
| Sensitivity: | 20 pg/mL |
| Applications: | ELISA |
| Assay Range: | 62.5 - 4,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Citrate Plasma) |
| Source: | E. coli |
| Accession #: | NP_000451 |
| Applications: | BA |
For use with catalog number DTP00B
| Applications: | ELISA, Ctrl |
| Source: | Sf 21 (baculovirus) |
| Accession #: | P40225 |
| Applications: | BA |
Analyzed by SEC-MALS. His-tag (HEK-293-expressed)
| Source: | HEK293 |
| Accession #: | P40225.1 |
| Applications: | BA |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: Thrombopoietin/THPO Antibody [NBP1-59293]](https://resources.bio-techne.com/images/products/Thrombopoietin-Antibody-Western-Blot-NBP1-59293-img0002.jpg "Western Blot: Thrombopoietin/THPO Antibody [NBP1-59293]")
| Assay Range: | 62.5 - 4,000 pg/mL |
| Applications: | ELISA |
| Assay Range: | 93.8 - 6,000 pg/mL |
| Applications: | ELISA |
