Biotin-LC-NAD+

Name: Biotin-LC-NAD+
Brand: Tocris Bioscience
SKU: 6572

Tocris Bioscience, part of Bio-Techne | Catalog # 6572

COA / SDS

Biotinylated analog of β-NAD+; commonly used reagent in LSD1 and PARP1 assays

Key Product Details

Description:	Biotinylated analog of β-NAD+; commonly used reagent in LSD1 and PARP1 assays
Alternative Names:	6-Biotin-17-NAD
Chemical Name:	β-Nicotinamide-N6-(2-(6-(6-[biotinyl]aminohexanoyl)aminohexanoyl)aminoethyl)adenine dinucleotide sodium salt
Purity:	≥95% (HPLC)
Molecular Weight:	1181.09

View Full Technical Details for Biotin-LC-NAD+

Technical Data
Citations

Biological Activity for Biotin-LC-NAD+

Biotin-LC-NAD+ is a biotinylated analog of β-NAD⁺. Commonly used reagent in LSD1 and PARP1 assays.

Technical Data for Biotin-LC-NAD+

M. Wt	1181.09
Formula	C₄₅H₆₇N₁₂NaO₁₈P₂S
Storage	Store at -80°C
Purity	≥95% (HPLC)
PubChem ID	134160253
InChi Key	LTPVGAFDQVQFRZ-NILCSMCPSA-M
Smiles	[H][C@]12CS[C@H]([C@]1(NC(N2)=O)[H])CCCCC(NCCCCCC(NCCCCCC(NCCNC3=C4N=CN(C4=NC=N3)[C@@H]5O[C@@H]([C@H]([C@H]5O)O)COP([O-])(OP([O-])(OC[C@H]6O[C@@H]([N+]7=CC=CC(C(N)=O)=C7)[C@@H]([C@@H]6O)O)=O)=O)=O)=O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Biotin-LC-NAD+

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
Solubility	water	11.81	10

Preparing Stock Solutions for Biotin-LC-NAD+

The following data is based on the product molecular weight 1181.09.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	8.47 mL	42.33 mL	84.67 mL
0.5 mM	1.69 mL	8.47 mL	16.93 mL
1 mM	0.85 mL	4.23 mL	8.47 mL
5 mM	0.17 mL	0.85 mL	1.69 mL

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Reconstitution Calculator

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References for Biotin-LC-NAD+

References are publications that support the biological activity of the product.

Dancy Azalysine analogues as probes for protein lysine deacetylation and demethylation. J.Am.Chem.Soc. 2012 PMID: 22352831