Fluorescein-NAD+

Name: Fluorescein-NAD+
Brand: Tocris Bioscience
SKU: 6574

Tocris Bioscience, part of Bio-Techne | Catalog # 6574

Citations (1)

COA / SDS

Fluorescent NAD+; substrate for ADP-ribosylation for use in PARP assays

Key Product Details

Description:	Fluorescent NAD⁺; substrate for ADP-ribosylation for use in PARP assays
Chemical Name:	β-Nicotinamide-N⁶-[2-[[6-[fluorescein]-amino]-2-oxohexyl-hexyl]amino]-2-oxoethyl]adenine dinucleotide
Molecular Weight:	1291.11

View Full Technical Details for Fluorescein-NAD+

Technical Data
Citations

Biological Activity for Fluorescein-NAD+

Fluorescein-NAD+ is a fluoroscein NAD⁺ is a substrate for ADP-ribosylation, providing a convenient non-isotopic alternative to radiolabelled NAD for use in PARP assays. Allows direct measurement of NAD-dependent enzymes, such as PARP, by fluorescence microscopy. Wavelengths are compatible with use as an acceptor dye in TR-FRET assays, together with the CoraFluor™ 1 (Cat. No. 7920) TR-FRET donor.

This product is a replacement for R&D Systems product 4673-500-01

81 μg is supplied as 250 μl of a 0.25 mM solution in water.

Technical Data for Fluorescein-NAD+

M. Wt	1291.11
Formula	C₅₆H₆₄N₁₀O₂₂P₂
Storage	Store at -80°C
InChi Key	QHUOJAOGTDUAPK-JDUNSKHUSA-N
Smiles	O=C(CCCCCNC(C1=CC(C(O)=O)=C(C2=C(C=C3)C(OC4=C2C=CC(O)=C4)=CC3=O)C=C1)=O)NCCCCCCNC(CNC5=C(N=CN6[C@@H]7O[C@@H]([C@H]([C@H]7O)O)COP(O)(OP(OC[C@H]8O[C@@H]([N+]9=CC=CC(C(N)=O)=C9)[C@H](O)[C@@H]8O)([O-])=O)=O)C6=NC=N5)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Fluorescein-NAD+

Solubility

Soluble in water (supplied pre-dissolved at a concentration of 0.25mM)

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Product Documents for Fluorescein-NAD+

COA

Certificate of Analysis

To download a Certificate of Analysis, please select a batch below.