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14-3-3 zeta Antibody (C2)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41869

Novus Biologicals, part of Bio-Techne
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NBP3-41869

Key Product Details

Species Reactivity

Human, Porcine

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # C2

Concentration

1 mg/ml

Product Specifications

Immunogen

Immunized with recombinant Human 14-3-3 zeta (Uniprot#: P63104; Met1-Asn245 (Uniprot#: P63104)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for 14-3-3 zeta Antibody (C2)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20ug/mL

Immunohistochemistry

5-20ug/mL

Western Blot

0.5-2ug/mL

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: 14-3-3 zeta

14-3-3 zeta is a protein that mediates signal transduction by binding to phosphoserine-containing proteins. The protein is widely expressed in various gray matter regions of the brain. Overexpression of the 14-3-3 zeta gene has been found to correlate with chemoresistance to anthracyclines and metastatis recurrence of human breast cancer. These effects are likely caused by an anti-apoptotic mechanism of 14-3-3 zeta during anthracycline treatment.

Alternate Names

1433 zeta, KCIP-1, YWHAZ

Gene Symbol

YWHAZ

Additional 14-3-3 zeta Products

Product Documents for 14-3-3 zeta Antibody (C2)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for 14-3-3 zeta Antibody (C2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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