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5-HT1F Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS3343

Novus Biologicals, part of Bio-Techne
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NLS3343

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Bat, Bovine, Canine, Chicken, Guinea Pig, Hamster, Monkey, Primate, Rabbit

Predicted:

Avian (100%), Chimpanzee (100%), Fish (94%), Guinea Pig (100%), Orangutan (100%), Xenopus (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Synthetic 17 amino acid peptide from C-terminus of human 5-HT1F.

Epitope

C-Terminus

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Opossum (88%), Equine (82%).

Specificity

Human 5-HT1F. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except HTR1E (71%), HTR1D (59%), HTR1B (59%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for 5-HT1F Antibody - BSA Free

Immunohistochemistry-Paraffin: 5-HT1F Antibody - BSA Free [NLS3343]

Immunohistochemistry-Paraffin: 5-HT1F Antibody - BSA Free [NLS3343]

Immunohistochemistry-Paraffin: 5-HT1F Antibody [NLS3343] - Analysis of anti-HTR1F / 5-HT1F antibody with human brain, cortex, neurons at dilution 2-3 ug/ml.

Applications for 5-HT1F Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

2 - 3 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: 5-HT1F

5HT1F, a Serotonin Receptor, is negatively coupled to adenylate cyclase. Selective 5HT1F agonists may prove therapeutic in the treatment of migraine headache, lacking the side effects associated with the agonists of the 5-HT1B and 5-HT1D receptors. Expression of the 5HT1F receptor has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen.

Long Name

5-Hydroxytryptamine Receptor 1F

Alternate Names

5HT1F, 5HT6, HTR1EL, HTR1F, MR77

Entrez Gene IDs

3355 (Human)

Gene Symbol

HTR1F

Additional 5-HT1F Products

Product Documents for 5-HT1F Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for 5-HT1F Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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