5-HT7 Antibody (SR1954)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22298

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22298-100ul
NBP3-22298-50ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1954

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all 5-HT7 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human 5-HT7 (Uniprot #: P34969)

Specificity

Detects endogenous levels of total 5-HT7

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for 5-HT7 Antibody (SR1954)

Western Blot: 5-HT7 Antibody (SR1954) [NBP3-22298] -

Western Blot: 5-HT7 Antibody (SR1954) [NBP3-22298] - Western blot analysis using NBP3-22298 in U-87MG cell lysate.

Applications for 5-HT7 Antibody (SR1954)

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: 5-HT7

Receptors for serotonin (5-hydroxytryptamine, 5-HT) are classified into seven major classes (5-HTR1-7), based on structural, functional and pharmacological criteria (Hoyer et al, 1994). The 5-HT7 receptor (5-HT7R) is a seven-transmembrane-domain G-protein-coupled receptor that has important roles in regulating diverse biological process in the central and peripheral nervous systems (reviewed in Hedlund and Sutcliffe, 2004). Receptors for serotonin (5-hydroxytryptamine, 5-HT) are classified into seven major classes (5-HT1-7), based on structural, functional and pharmacological criteria (Hoyer et al, 1994). Sequence alignment shows a high degree of interspecies 5-HT7R homology (>90%), and a low homology with other 5-HTRs (

Long Name

5-Hydroxytryptamine Receptor 7

Alternate Names

5-HT-X, 5HT7, HTR7

Gene Symbol

HTR7

Additional 5-HT7 Products

Product Documents for 5-HT7 Antibody (SR1954)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for 5-HT7 Antibody (SR1954)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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